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肺军团菌病30天死亡率的决定因素:合并感染有影响吗?

Determinant of 30-Day Mortality of Pulmonary Legionellosis: Do Coinfections Matter?

作者信息

Matsuo Takahiro, Wurster Sebastian, Jiang Ying, Tarrand Jeffrey, Evans Scott E, Kontoyiannis Dimitrios P

机构信息

Department of Infectious Diseases, Infection Control and Employee Health, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.

Section of Clinical Microbiology and Virology, Division of Pathology and Laboratory Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.

出版信息

Open Forum Infect Dis. 2024 Sep 12;11(9):ofae529. doi: 10.1093/ofid/ofae529. eCollection 2024 Sep.

Abstract

We retrospectively reviewed 64 cases of cancer with pulmonary legionellosis ( in 73%). Nearly all patients received -active antibiotics, yet 30-day mortality was 23%. Independent predictors of 30-day mortality were hyponatremia, bilateral lung involvement, and Sequential Organ Failure Assessment score ≥5. Lung coinfections were common (31%) but did not significantly increase mortality.

摘要

我们回顾性分析了64例合并肺军团菌病的癌症患者(占73%)。几乎所有患者都接受了抗感染治疗,但30天死亡率为23%。30天死亡率的独立预测因素为低钠血症、双侧肺部受累以及序贯器官衰竭评估评分≥5。肺部合并感染很常见(31%),但并未显著增加死亡率。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8c10/11420677/5ab4bf0dd373/ofae529_ga.jpg

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