Buchanan T A, Unterman T G, Metzger B E
Clin Perinatol. 1985 Oct;12(3):625-50.
This article is divided into three sections. "Metabolic Adaptations to Normal Pregnancy" describes the changes in intermediary metabolism that normally attend pregnancy and relates these changes to states of insulin deficiency--i.e., diabetes. "Implications for the Conceptus" reviews our current understanding of how the metabolic derrangements that characterize maternal diabetes may affect embryo and fetal development. "Management" details practical aspects of a management program aimed at normalizing pregnancy outcome for women with both pregestational and gestational diabetes mellitus.
本文分为三个部分。“正常妊娠的代谢适应”描述了正常妊娠期间中间代谢的变化，并将这些变化与胰岛素缺乏状态（即糖尿病）联系起来。“对胚胎的影响”回顾了我们目前对母体糖尿病特征性代谢紊乱如何影响胚胎和胎儿发育的理解。“管理”详细介绍了旨在使孕前和妊娠期糖尿病女性的妊娠结局正常化的管理计划的实际方面。
