• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

将健康的社会决定因素纳入机器学习驱动的糖尿病病例管理决策支持中:一项序贯混合方法研究的方案。

Integrating Social Determinants of Health in Machine Learning-Driven Decision Support for Diabetes Case Management: Protocol for a Sequential Mixed Methods Study.

机构信息

School of Health Professions, University of Alabama at Birmingham, Birmingham, AL, United States.

Department of Quality and Patient Safety, University of Alabama at Birmingham Medicine, Birmingham, AL, United States.

出版信息

JMIR Res Protoc. 2024 Sep 25;13:e56049. doi: 10.2196/56049.

DOI:10.2196/56049
PMID:39321449
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11464948/
Abstract

BACKGROUND

The use of both clinical factors and social determinants of health (SDoH) in referral decision-making for case management may improve optimal use of resources and reduce outcome disparities among patients with diabetes.

OBJECTIVE

This study proposes the development of a data-driven decision-support system incorporating interactions between clinical factors and SDoH into an algorithm for prioritizing who receives case management services. The paper presents a design for prediction validation and preimplementation assessment that uses a mixed methods approach to guide the implementation of the system.

METHODS

Our study setting is a large, tertiary care academic medical center in the Deep South of the United States, where SDoH contribute to disparities in diabetes-specific hospitalizations and emergency department (ED) visits. This project will develop an interpretable artificial intelligence model for a population with diabetes using SDoH and clinical data to identify which posthospitalization cases have a higher likelihood of subsequent ED use. The electronic health record data collected for the study include demographics, SDoH, comorbidities, hospitalization-related factors, laboratory test results, and medication use to predict posthospitalization ED visits. Subsequently, a mixed methods approach will be used to validate prediction outcomes and develop an implementation strategy from insights into patient outcomes from case managers, clinicians, and quality and patient safety experts.

RESULTS

As of December 2023, we had abstracted data on 174,871 inpatient encounters between January 2018 and September 2023, involving 89,355 unique inpatients meeting inclusion criteria. Both clinical and SDoH data items were included for these patient encounters. In total, 85% of the inpatient visits (N=148,640) will be used for training (learning from the data) and the remaining 26,231 inpatient visits will be used for mixed-methods validation (testing).

CONCLUSIONS

By integrating a critical suite of SDoH with clinical data related to diabetes, the proposed data-driven risk stratification model can enable individualized risk estimation and inform health professionals (eg, case managers) about the risk of patients' upcoming ED use. The prediction outcome could potentially automate case management referrals, helping to better prioritize services. By taking a mixed methods approach, we aim to align the model with the hospital's specific quality and patient safety considerations for the quality of patient care and the optimization of case management resource allocation.

INTERNATIONAL REGISTERED REPORT IDENTIFIER (IRRID): DERR1-10.2196/56049.

摘要

背景

在为病例管理制定转介决策时,同时使用临床因素和健康的社会决定因素(SDoH),可能会提高资源的最佳利用,并减少糖尿病患者之间的结果差异。

目的

本研究旨在开发一种数据驱动的决策支持系统,将临床因素和 SDoH 之间的相互作用纳入算法中,以便对接受病例管理服务的人员进行优先级排序。本文提出了一种预测验证和实施前评估的设计,该设计采用混合方法来指导系统的实施。

方法

我们的研究地点是美国南部的一家大型三级保健学术医疗中心,那里的 SDoH 导致了糖尿病患者的特定住院和急诊就诊方面的差异。该项目将使用 SDoH 和临床数据为糖尿病患者开发一个可解释的人工智能模型,以识别哪些出院后病例更有可能随后使用急诊。为研究收集的电子健康记录数据包括人口统计学数据、SDoH、合并症、住院相关因素、实验室检测结果和药物使用情况,以预测出院后的急诊就诊情况。随后,将采用混合方法从病例管理员、临床医生和质量与患者安全专家对患者结局的见解中验证预测结果并制定实施策略。

结果

截至 2023 年 12 月,我们已经从 2018 年 1 月至 2023 年 9 月期间的 174871 次住院患者就诊中提取了数据,涉及符合纳入标准的 89355 名住院患者。这些患者就诊均包括临床和 SDoH 数据项。总共,85%的住院就诊(N=148640)将用于培训(从数据中学习),其余 26231 次住院就诊将用于混合方法验证(测试)。

结论

通过将一套关键的 SDoH 与与糖尿病相关的临床数据相结合,所提出的数据驱动的风险分层模型可以实现个体化风险估计,并使卫生专业人员(例如,病例管理员)了解患者即将使用急诊的风险。预测结果可能会使病例管理转介自动化,有助于更好地确定服务优先级。通过采用混合方法,我们旨在使模型与医院特定的质量和患者安全考虑因素保持一致,以确保患者护理质量和病例管理资源分配的最优化。

国际注册报告标识符(IRRID):DERR1-10.2196/56049。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e64f/11464948/97d407e30c75/resprot_v13i1e56049_fig5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e64f/11464948/31f53fa281ff/resprot_v13i1e56049_fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e64f/11464948/8ad2afd75a96/resprot_v13i1e56049_fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e64f/11464948/47426d4a3c79/resprot_v13i1e56049_fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e64f/11464948/168c543f0784/resprot_v13i1e56049_fig4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e64f/11464948/97d407e30c75/resprot_v13i1e56049_fig5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e64f/11464948/31f53fa281ff/resprot_v13i1e56049_fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e64f/11464948/8ad2afd75a96/resprot_v13i1e56049_fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e64f/11464948/47426d4a3c79/resprot_v13i1e56049_fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e64f/11464948/168c543f0784/resprot_v13i1e56049_fig4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e64f/11464948/97d407e30c75/resprot_v13i1e56049_fig5.jpg

相似文献

1
Integrating Social Determinants of Health in Machine Learning-Driven Decision Support for Diabetes Case Management: Protocol for a Sequential Mixed Methods Study.将健康的社会决定因素纳入机器学习驱动的糖尿病病例管理决策支持中:一项序贯混合方法研究的方案。
JMIR Res Protoc. 2024 Sep 25;13:e56049. doi: 10.2196/56049.
2
Piloting a Clinical Decision Support Tool to Identify Patients With Social Needs and Provide Navigation Services and Referral to Community-Based Organizations: Protocol for a Randomized Controlled Trial.为识别有社会需求的患者并提供导航服务和向社区组织转介而试行临床决策支持工具:一项随机对照试验方案。
JMIR Res Protoc. 2024 Jul 23;13:e57316. doi: 10.2196/57316.
3
A Machine Learning Approach to Support Urgent Stroke Triage Using Administrative Data and Social Determinants of Health at Hospital Presentation: Retrospective Study.一种基于机器学习的方法,利用医院就诊时的行政数据和健康社会决定因素来支持紧急脑卒中分诊:回顾性研究。
J Med Internet Res. 2023 Jan 30;25:e36477. doi: 10.2196/36477.
4
Understanding the Role of a Technology and EMR-based Social Determinants of Health Screening Tool and Community-based Resource Connections in Health Care Resource Utilization.了解基于技术和电子病历的社会决定因素健康筛查工具以及社区资源链接在医疗资源利用中的作用。
Med Care. 2023 Jul 1;61(7):423-430. doi: 10.1097/MLR.0000000000001800. Epub 2022 Dec 12.
5
6
Folic acid supplementation and malaria susceptibility and severity among people taking antifolate antimalarial drugs in endemic areas.在流行地区,服用抗叶酸抗疟药物的人群中,叶酸补充剂与疟疾易感性和严重程度的关系。
Cochrane Database Syst Rev. 2022 Feb 1;2(2022):CD014217. doi: 10.1002/14651858.CD014217.
7
Linking Electronic Health Records and In-Depth Interviews to Inform Efforts to Integrate Social Determinants of Health Into Health Care Delivery: Protocol for a Qualitative Research Study.将电子健康记录与深入访谈相联系,为将健康的社会决定因素纳入医疗服务的努力提供信息:一项定性研究的方案
JMIR Res Protoc. 2022 Mar 11;11(3):e36201. doi: 10.2196/36201.
8
Prediction of In-hospital Mortality in Emergency Department Patients With Sepsis: A Local Big Data-Driven, Machine Learning Approach.急诊科脓毒症患者院内死亡率的预测:一种基于本地大数据驱动的机器学习方法。
Acad Emerg Med. 2016 Mar;23(3):269-78. doi: 10.1111/acem.12876. Epub 2016 Feb 13.
9
Leveraging Large-Scale Electronic Health Records and Interpretable Machine Learning for Clinical Decision Making at the Emergency Department: Protocol for System Development and Validation.利用大规模电子健康记录和可解释机器学习进行急诊科临床决策:系统开发与验证方案
JMIR Res Protoc. 2022 Mar 25;11(3):e34201. doi: 10.2196/34201.
10
Are Detailed, Patient-level Social Determinant of Health Factors Associated With Physical Function and Mental Health at Presentation Among New Patients With Orthopaedic Conditions?详细的患者层面的健康社会决定因素是否与新骨科患者就诊时的身体功能和心理健康相关?
Clin Orthop Relat Res. 2023 May 1;481(5):912-921. doi: 10.1097/CORR.0000000000002446. Epub 2022 Oct 6.

引用本文的文献

1
Inflammatory Biomarkers as Indicators of Social Risk in Rural Health: Insights From Ecuador and the Philippine GIDA Experience.炎症生物标志物作为农村健康社会风险指标:来自厄瓜多尔和菲律宾全球疾病负担评估(GIDA)经验的见解。
J Prim Care Community Health. 2025 Jan-Dec;16:21501319251357359. doi: 10.1177/21501319251357359. Epub 2025 Jul 16.

本文引用的文献

1
Area-level social determinants of health and individual-level social risks: Assessing predictive ability and biases in social risk screening.地区层面的健康社会决定因素与个体层面的社会风险:评估社会风险筛查中的预测能力和偏差。
J Clin Transl Sci. 2023 Nov 10;7(1):e257. doi: 10.1017/cts.2023.680. eCollection 2023.
2
Community-level social determinants of health and pregestational and gestational diabetes.社区层面的健康社会决定因素与孕前和妊娠期糖尿病。
Am J Obstet Gynecol MFM. 2024 Feb;6(2):101249. doi: 10.1016/j.ajogmf.2023.101249. Epub 2023 Dec 7.
3
Improving health outcomes of people with diabetes: target setting for the WHO Global Diabetes Compact.
提高糖尿病患者的健康结果:世卫组织全球糖尿病契约的目标设定。
Lancet. 2023 Apr 15;401(10384):1302-1312. doi: 10.1016/S0140-6736(23)00001-6. Epub 2023 Mar 14.
4
Recent Trends in Diabetes-Associated Hospitalizations in the United States.美国糖尿病相关住院治疗的近期趋势。
J Clin Med. 2022 Nov 9;11(22):6636. doi: 10.3390/jcm11226636.
5
Diabetes associated with higher health care utilization and poor outcomes after COPD-related hospitalizations.糖尿病与 COPD 相关住院后更高的医疗保健利用率和较差的结局相关。
Am J Manag Care. 2022 Sep 1;28(9):e325-e332. doi: 10.37765/ajmc.2022.89225.
6
Association Between Social Vulnerability Index and Cardiovascular Disease: A Behavioral Risk Factor Surveillance System Study.社会脆弱性指数与心血管疾病的关联:一项行为风险因素监测系统研究。
J Am Heart Assoc. 2022 Aug 2;11(15):e024414. doi: 10.1161/JAHA.121.024414. Epub 2022 Jul 29.
7
Racial/ethnic and socioeconomic disparities in the use of newer diabetes medications in the Look AHEAD study.“展望”研究中新型糖尿病药物使用方面的种族/族裔及社会经济差异。
Lancet Reg Health Am. 2022 Feb;6. doi: 10.1016/j.lana.2021.100111. Epub 2021 Nov 8.
8
Association of Area-Level Socioeconomic Deprivation With Hypoglycemic and Hyperglycemic Crises in US Adults With Diabetes.与美国成年人糖尿病患者的低血糖和高血糖危象相关的地区社会经济剥夺程度的相关性。
JAMA Netw Open. 2022 Jan 4;5(1):e2143597. doi: 10.1001/jamanetworkopen.2021.43597.
9
Delphi methodology in healthcare research: How to decide its appropriateness.医疗保健研究中的德尔菲法:如何确定其适用性。
World J Methodol. 2021 Jul 20;11(4):116-129. doi: 10.5662/wjm.v11.i4.116.
10
Effect of Diabetes Mellitus on 30 and 90-Day Readmissions of Patients With Heart Failure.糖尿病对心力衰竭患者 30 天和 90 天再入院的影响。
Am J Cardiol. 2021 Sep 15;155:78-85. doi: 10.1016/j.amjcard.2021.06.016. Epub 2021 Jul 16.