Cui Jialu, Lin Lin, Hao Feiran, Shi Zhuo, Gao Yehui, Yang Tingyu, Yang Chunqi, Wu Xiangjun, Gao Rong, Ru Yi, Li Fangyang, Xiao Chengrong, Gao Yue, Wang Yuguang
Institute of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin, China.
Department of Pharmaceutical Sciences, Beijing Institute of Radiation Medicine, Beijing, China.
Front Pharmacol. 2024 Sep 11;15:1415265. doi: 10.3389/fphar.2024.1415265. eCollection 2024.
Epimedium Folium has been extensively utilized for medicinal purposes in China for a significant period. This review undertakes a comprehensive examination of literature pertaining to Epimedium and its metabolites over the past decade, drawing from databases such as PubMed. Through meticulous organization and synthesis of pertinent research findings, including disease models, pharmacological effects, and related aspects, this narrative review sheds light on the principal pharmacological activities and associated mechanisms of Epimedium in safeguarding the reproductive system, promoting bone health, mitigating inflammation, and combating tumors and viral infections. Consequently, this review contributes to a more profound comprehension of the recent advances in Epimedium research.
淫羊藿在中国已被广泛用于药用很长一段时间。本综述对过去十年中来自PubMed等数据库的有关淫羊藿及其代谢产物的文献进行了全面研究。通过精心组织和综合相关研究结果,包括疾病模型、药理作用及相关方面,本叙述性综述揭示了淫羊藿在保护生殖系统、促进骨骼健康、减轻炎症以及对抗肿瘤和病毒感染方面的主要药理活性及相关机制。因此,本综述有助于更深入地理解淫羊藿研究的最新进展。