昼夜节律紊乱对疼痛的影响。
Implications of Disrupted Circadian Rhythms on Pain.
作者信息
Bumgarner Jacob R, Nelson Randy J
机构信息
Department of Neuroscience, Rockefeller Neuroscience Institute, West Virginia University, Morgantown, WV 26505, USA.
出版信息
J Psychiatr Brain Sci. 2021;6(4). doi: 10.20900/jpbs.20210014. Epub 2021 Aug 6.
Abstract
Pain is regulated by circadian rhythms. Daily fluctuations in pain thresholds are observed in health and disease. Disruptions to the circadian and pain systems may initiate a detrimental feedback loop between the two systems. The relationship between the pain and circadian systems is briefly reviewed to highlight a perspective on the need to consider disrupted circadian rhythms in the treatment of pain.
摘要
疼痛受昼夜节律调节。在健康和疾病状态下均可观察到疼痛阈值的每日波动。昼夜节律系统与疼痛系统的紊乱可能会在这两个系统之间引发有害的反馈循环。本文简要回顾了疼痛与昼夜节律系统之间的关系，以强调在疼痛治疗中考虑昼夜节律紊乱必要性的观点。
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