Tanishita K, Tanasawa I, Yamaguchi T, Sugawara M
Pflugers Arch. 1985 Sep;405(2):83-90. doi: 10.1007/BF00584527.
The values of effective permeability (Krogh's diffusion coefficient) for carbon dioxide have been measured in horizontal stationary layers of whole blood and hemoglobin solutions in quasi-steady state, with the goal of understanding the specific nature of facilitated diffusion of carbon dioxide occurring in these media. The average partial pressure of carbon dioxide within the layer ranged from 0.74 kPa (5.6 mm Hg) to 15.7 kPa (118 mm Hg). Facilitation effects were significant in hemolysed blood and in hemoglobin solutions at low pCO2; the facilitation factor was up to 2.3. Facilitation effects were considerably less for intact blood; the facilitation factor of intact blood with hematocrit 45% was 0.3. The presence of the red cell membrane appears to have a negative effect on facilitation of carbon dioxide transport.
为了了解二氧化碳在这些介质中发生的易化扩散的具体性质，已在准稳态下对全血和血红蛋白溶液的水平静止层中二氧化碳的有效渗透率（克罗格扩散系数）值进行了测量。层内二氧化碳的平均分压范围为0.74千帕（5.6毫米汞柱）至15.7千帕（118毫米汞柱）。在低二氧化碳分压下，溶血血液和血红蛋白溶液中的易化作用显著；易化因子高达2.3。对于完整血液，易化作用要小得多；血细胞比容为45%的完整血液的易化因子为0.3。红细胞膜的存在似乎对二氧化碳运输的易化有负面影响。
