Khokhlov A N, Golovina M E, Chirkova E Iu, Nadzharian T L
Tsitologiia. 1985 Sep;27(9):1070-5.
With the help of the earlier devised model of cultured cell growth kinetics it is shown that the "plateau" level on the growth curve of Chinese hamster cells decreased proportionally to a dose of the agent applied after a short-term treatment by gamma-radiation or by alkylating agent thiophosphamide. The analysis of our own and literature data enabled us to propose that the lowering of the growth curve may testify to the geropromoter character (i.e. manifesting in ageing promoting) of the investigated factor action. As the low-frequency electromagnetic field induces similar changes in the growth curve, it is related (together with both the above factors investigated) to geropromoters.
借助早期设计的培养细胞生长动力学模型表明，中国仓鼠细胞生长曲线上的“平台”水平，在经γ射线或烷化剂硫磷酰胺短期处理后，与所施加试剂的剂量成比例降低。对我们自己的数据和文献数据的分析使我们能够提出，生长曲线的降低可能证明所研究因素作用具有促老化特性（即在促进衰老方面表现出来）。由于低频电磁场在生长曲线中诱导出类似变化，它（与上述两个研究因素一起）与促老化因素相关。
