Key Laboratory of Clinical Laboratory Medicine of Guangxi Department of Education, Department of Clinical Laboratory, The First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, China.
Medicine (Baltimore). 2024 Sep 27;103(39):e39788. doi: 10.1097/MD.0000000000039788.
To evaluate the alarm notification of artificial intelligence in detecting parasites on the KU-F40 Fully Automatic Feces Analyzer and provide a reference for clinical diagnosis in parasite diseases. A total of 1030 fecal specimens from patients in our hospital from May to June 2023 were collected, and parasite detection studies were conducted using the KU-F40 automated feces analyzer (normal mode method, floating-sedimentation mode method), acid-ether sedimentation method, and direct smear microscopy method, respectively. The positive detection rate of parasites in the 1030 fecal specimens was 22.9% (236 cases), of which the KU-F40 normal mode method had a detection rate of 16.3% (168 cases), the acid-ether sedimentation method had a detection rate of 19.0% (196 cases), and the direct smear microscopy method had a detection rate of 13.1% (135 cases). The detection rates of the first 2 methods were higher than those of the direct smear microscopy method, and the difference was statistically significant (P < .05). The detection rate of the KU-F40 floating-sedimentation mode method was 11.9% (123 cases), which was lower than that of the direct smear microscopy, and the difference was not statistically significant (P > .05). The sensitivity of the KU-F40 normal mode method, acid-ether sedimentation method, direct smear microscopy method, and the KU-F40 floating-sedimentation mode method were 71.2%, 83.1%, 57.2%, and 52.1%, respectively, and the specificity was 94.7%, 100%, 100%, and 97.7%, respectively. The coincidence rates of the KU-F40 normal mode method was 90.78%, with Kappa values of 0.633. The positive detection rate of parasites using the KU-F40 normal mode method is higher than that using the direct smear microscopy method. It has high sensitivity and specificity and has advantages such as high automation and fast detection speed. It can replace the microscopy method for routine screening and has higher clinical application value in the diagnosis of intestinal parasitic diseases.
为了评估人工智能在 KU-F40 全自动粪便分析器上检测寄生虫的报警通知,并为寄生虫病的临床诊断提供参考。收集了 2023 年 5 月至 6 月我院患者的 1030 份粪便标本,分别采用 KU-F40 全自动粪便分析仪(正常模式法、浮聚沉淀模式法)、酸醚沉淀法和直接涂片显微镜法进行寄生虫检测研究。1030 份粪便标本中寄生虫的阳性检出率为 22.9%(236 例),其中 KU-F40 正常模式法检出率为 16.3%(168 例),酸醚沉淀法检出率为 19.0%(196 例),直接涂片显微镜法检出率为 13.1%(135 例)。前 2 种方法的检出率高于直接涂片显微镜法,差异有统计学意义(P<0.05)。KU-F40 浮聚沉淀模式法的检出率为 11.9%(123 例),低于直接涂片显微镜法,差异无统计学意义(P>0.05)。KU-F40 正常模式法、酸醚沉淀法、直接涂片显微镜法和 KU-F40 浮聚沉淀模式法的灵敏度分别为 71.2%、83.1%、57.2%和 52.1%,特异性分别为 94.7%、100%、100%和 97.7%。KU-F40 正常模式法的符合率为 90.78%,Kappa 值为 0.633。KU-F40 正常模式法检测寄生虫的阳性检出率高于直接涂片显微镜法。它具有灵敏度高、特异性高、自动化程度高、检测速度快等优点,可替代显微镜法进行常规筛查,在寄生虫性肠病的诊断中具有较高的临床应用价值。