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KU-F40全自动粪便分析仪在粪便寄生虫检测中的临床应用价值:一项大样本回顾性研究。

The clinical application value of the KU-F40 fully automatic fecal analyzer for the detection of fecal parasites: A large-sample retrospective study.

作者信息

Huang Chu, Huang Yunhua, Lin Faquan, Liao Lin

机构信息

Key Laboratory of Clinical Laboratory Medicine of Guangxi Department of Education, Department of Clinical Laboratory, The First Affiliated Hospital of Guangxi Medical University, Nanning, 530021, Guangxi, China.

出版信息

Sci Rep. 2025 Jul 7;15(1):24172. doi: 10.1038/s41598-025-09935-7.

Abstract

Improving the sensitivity of parasite detection is an urgent task for global public health. The traditional manual microscopy method still has some shortcomings in fecal parasite detection. This study aimed to evaluate the clinical application value of the KU-F40 fully automated fecal analyzer in fecal parasite detection by comparing the fecal detection results of the manual microscopy method with those of the KU-F40 instrumental method. Fecal test results were collected from January to June 2023 and January to June 2024, and divided into manual microscopy group (n = 51,627) and KU-F40 instrumental group (n = 50,606) according to methodology. The detection levels and species of parasites detected by the two methods were retrospectively analyzed. The KU-F40 instrumental group had a higher parasite detection level (8.74%) than the manual microscopy group (2.81%), with statistically significant differences between groups (χ = 1661.333, P < 0.05). Five species of parasites were detected by the manual microscopy method and nine species of parasites were detected by the KU-F40 instrumental method, of which the detection levels of Clonorchis sinensis eggs, hookworm eggs and Blastocystis hominis were higher than those of the manual microscopy method, with statistically significant differences (P < 0.05). Although the detection levels of tapeworm eggs and Strongyloides stercoralis were also higher than the manual microscopy method, the differences were not statistically significant (P > 0.05). The KU-F40 fully automatic fecal analyzer has a higher sensitivity to parasite detection and holds significant clinical application value in the detection of fecal parasites. With the combination of manual re-examination, the accuracy of test results can be significantly improved.

摘要

提高寄生虫检测的灵敏度是全球公共卫生的一项紧迫任务。传统的手工显微镜检查方法在粪便寄生虫检测中仍存在一些缺点。本研究旨在通过比较手工显微镜检查方法与KU-F40仪器法的粪便检测结果,评估KU-F40全自动粪便分析仪在粪便寄生虫检测中的临床应用价值。收集了2023年1月至6月和2024年1月至6月的粪便检测结果,并根据方法分为手工显微镜检查组(n = 51627)和KU-F40仪器检查组(n = 50606)。回顾性分析了两种方法检测到的寄生虫的检测水平和种类。KU-F40仪器检查组的寄生虫检测水平(8.74%)高于手工显微镜检查组(2.81%),组间差异有统计学意义(χ = 1661.333,P < 0.05)。手工显微镜检查方法检测到5种寄生虫,KU-F40仪器法检测到9种寄生虫,其中华支睾吸虫卵、钩虫卵和人芽囊原虫的检测水平高于手工显微镜检查方法,差异有统计学意义(P < 0.05)。虽然绦虫卵和粪类圆线虫的检测水平也高于手工显微镜检查方法,但差异无统计学意义(P > 0.05)。KU-F40全自动粪便分析仪对寄生虫检测具有较高的灵敏度,在粪便寄生虫检测中具有重要的临床应用价值。结合手工复查可显著提高检测结果的准确性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c657/12234752/cdc1294089a3/41598_2025_9935_Fig1_HTML.jpg

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