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今天无痛,明天虚弱:一例因滥用双氯芬酸导致的电解质紊乱。

Pain-free today, weak tomorrow: a case of electrolyte disorder due to diclofenac misuse.

机构信息

Department of Public Health, Chair of Nephrology, University Federico II of Naples, Via Pansini 5, Naples, 80131, Italy.

Department of Neurosciences, Reproductive and Odontostomatological Sciences, University of Naples Federico II, via Pansini,5, Naples, 80131, Italy.

出版信息

BMC Nephrol. 2024 Sep 27;25(1):317. doi: 10.1186/s12882-024-03759-9.

Abstract

BACKGROUND

The nephrotoxic effects of non-steroidal anti-inflammatory drugs (NSAIDs) are widely acknowledged. In particular, diclofenac is the most commonly prescribed NSAIDs, but no previous findings of electrolyte disturbances were reported following its administration.

CASE REPORT

We presented the case of a man who experienced significant weakness associated with severe deficiencies in potassium, calcium, and magnesium after misusing diclofenac because of severe back pain.

CONCLUSIONS

This case emphasizes the need of awareness about the electrolyte imbalances and electrolyte disturbances associated with the misuse of diclofenac, which is a widely available drug. This is a case report which does not need a Clinical Trial Number.

摘要

背景

非甾体抗炎药(NSAIDs)的肾毒性作用是众所周知的。特别是,双氯芬酸是最常被开的 NSAIDs,但在使用后没有发现电解质紊乱的先前发现。

病例报告

我们报告了一例因严重背痛滥用双氯芬酸后出现严重低钾、低钙和低镁相关显著无力的病例。

结论

本病例强调了对与滥用双氯芬酸相关的电解质失衡和电解质紊乱的认识的必要性,因为双氯芬酸是一种广泛使用的药物。这是一个病例报告,不需要临床试验编号。

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