Suppr超能文献

今天无痛,明天虚弱:一例因滥用双氯芬酸导致的电解质紊乱。

Pain-free today, weak tomorrow: a case of electrolyte disorder due to diclofenac misuse.

机构信息

Department of Public Health, Chair of Nephrology, University Federico II of Naples, Via Pansini 5, Naples, 80131, Italy.

Department of Neurosciences, Reproductive and Odontostomatological Sciences, University of Naples Federico II, via Pansini,5, Naples, 80131, Italy.

出版信息

BMC Nephrol. 2024 Sep 27;25(1):317. doi: 10.1186/s12882-024-03759-9.

Abstract

BACKGROUND

The nephrotoxic effects of non-steroidal anti-inflammatory drugs (NSAIDs) are widely acknowledged. In particular, diclofenac is the most commonly prescribed NSAIDs, but no previous findings of electrolyte disturbances were reported following its administration.

CASE REPORT

We presented the case of a man who experienced significant weakness associated with severe deficiencies in potassium, calcium, and magnesium after misusing diclofenac because of severe back pain.

CONCLUSIONS

This case emphasizes the need of awareness about the electrolyte imbalances and electrolyte disturbances associated with the misuse of diclofenac, which is a widely available drug. This is a case report which does not need a Clinical Trial Number.

摘要

背景

非甾体抗炎药(NSAIDs)的肾毒性作用是众所周知的。特别是,双氯芬酸是最常被开的 NSAIDs,但在使用后没有发现电解质紊乱的先前发现。

病例报告

我们报告了一例因严重背痛滥用双氯芬酸后出现严重低钾、低钙和低镁相关显著无力的病例。

结论

本病例强调了对与滥用双氯芬酸相关的电解质失衡和电解质紊乱的认识的必要性,因为双氯芬酸是一种广泛使用的药物。这是一个病例报告,不需要临床试验编号。

相似文献

3
Skin necrosis after self-administered intramuscular diclofenac.自行肌内注射双氯芬酸后皮肤坏死。
J Plast Reconstr Aesthet Surg. 2010 Jan;63(1):e4-5. doi: 10.1016/j.bjps.2009.01.049. Epub 2009 Feb 28.
5
Nonsteroidal anti-inflammatory drugs (NSAIDs) for acute renal colic.用于急性肾绞痛的非甾体抗炎药
Cochrane Database Syst Rev. 2025 Mar 14;3(3):CD006027. doi: 10.1002/14651858.CD006027.pub3.
7
Multiple diclofenac-induced adverse effects.双氯芬酸引起的多种不良反应。
Am J Gastroenterol. 2000 Oct;95(10):2988-9. doi: 10.1111/j.1572-0241.2000.03218.x.

本文引用的文献

7
Action of diclofenac on kidney mitochondria and cells.双氯芬酸对肾脏线粒体和细胞的作用。
Biochem Biophys Res Commun. 2006 Sep 22;348(2):494-500. doi: 10.1016/j.bbrc.2006.07.089. Epub 2006 Jul 28.
10
Mechanism of action of anti-inflammatory drugs.抗炎药物的作用机制。
Scand J Rheumatol Suppl. 1996;102:9-21. doi: 10.3109/03009749609097226.

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验