Panzeri Daniele, Perina Michela, Biffi Emilia, Semino Martina, Diella Eleonora, Caprì Tindara
Scientific Institute IRCCS Eugenio Medea, Via Don Luigi Monza, 20, Bosisio Parini, 23842 Lecco, Italy.
CARI (Airett Center Innovation and Research), Vicolo Volto S. Luca, 16, 37100 Verona, Italy.
Children (Basel). 2024 Sep 11;11(9):1110. doi: 10.3390/children11091110.
BACKGROUND/OBJECTIVES: Rett syndrome is a rare neurodevelopmental disorder that can severely affect motor functioning, particularly walking. Previous training programs proposed treadmills as tools to increase walking endurance of patients with Rett syndrome, but these trainings did not include virtual reality (VR). The aim of this study was to assess the feasibility of a short treadmill training coupled to VR in girls with Rett syndrome.
Nine patients with Rett syndrome underwent a 3-day treadmill walking program performed in semi-immersive VR. During the training, the happiness index and performance metrics were collected. At the end of the training parents filled out the Suitability Evaluation Questionnaire (SEQ) and, when feasible, patients underwent a gait assessment.
All the subjects recruited performed the three GRAIL sessions and parents showed a good satisfaction and considered the integration of treadmill and VR a good possibility for future rehabilitative programs. Participants showed greater satisfaction in environments requiring walking and their attention increased during training sessions, hypothesizing the feasibility of longer trainings with treadmill and VR. Data collected from gait analysis provided insights, although preliminary, concerning differences in gait pattern amongst the recruited subjects.
Despite the small sample size and limited training duration, the paper suggests that a walking training with a treadmill combined with VR can represent a new strategy for Rett rehabilitation.
背景/目的：雷特综合征是一种罕见的神经发育障碍，会严重影响运动功能，尤其是行走能力。以往的训练方案建议使用跑步机来提高雷特综合征患者的行走耐力，但这些训练并未包含虚拟现实（VR）技术。本研究的目的是评估在患有雷特综合征的女孩中，短期跑步机训练与VR相结合的可行性。
9名雷特综合征患者在半沉浸式VR环境中进行了为期3天的跑步机行走训练。训练过程中收集了快乐指数和表现指标。训练结束时，家长填写了适用性评估问卷（SEQ），并且在可行的情况下，患者接受了步态评估。
所有招募的受试者都完成了三个阶段的训练，家长表示满意度较高，并认为跑步机与VR的结合对未来的康复计划是一个很好的选择。参与者在需要行走的环境中表现出更高的满意度，并且在训练过程中注意力有所提高，这表明进行更长时间的跑步机和VR训练具有可行性。从步态分析收集的数据虽初步，但提供了有关所招募受试者步态模式差异的见解。
尽管样本量小且训练时间有限，但本文表明跑步机与VR相结合的行走训练可以成为雷特综合征康复的一种新策略。
