Soleymani Fatemeh, Pérez-Albacete Martínez Carlos, Makiabadi Mehrdad, Maté Sánchez de Val José Eduardo
Health Sciences PhD Program, UCAM-Universidad Católica San Antonio de Murcia, Campus de los Jerónimos nº135, Guadalupe, 30107 Murcia, Spain.
Department of Biomaterials Engineering, Faculty of Health Sciences, UCAM-Universidad Católica San Antonio de Murcia, Guadalupe, 30107 Murcia, Spain.
Antibiotics (Basel). 2024 Sep 8;13(9):859. doi: 10.3390/antibiotics13090859.
Antibiotic resistance is a critical issue today, necessitating the monitoring of antibiotic usage across various sectors. To determine the defined daily doses (DDDs) of antibiotics prescribed by dentists globally, a comprehensive search was conducted in PubMed, ProQuest, ScienceDirect, Web of Science, Scopus, and EBSCOhost, resulting in the inclusion of 15 documents in this scoping review. The DDD per 1000 inhabitants per day (DID) for oral antibiotics prescribed by dentists for the studied countries was generally below 2.11, with the exception of South Korea, which had a DDD per 1000 patients per day (DPD) of less than 6.97. Most countries, except Croatia and Belgium, demonstrated a decreasing trend in DID before the COVID-19 pandemic, but restrictions during the pandemic led to an increase in these numbers. Penicillin-derived antibiotics were the most commonly prescribed antibiotic among dentists in most countries. This study highlights significant gaps and missing data regarding antibiotics prescribed by dentists worldwide. However, it also indicates that the publication of guidelines, education, and evaluation of antibiotic use can lead to more controlled and appropriate prescriptions among dental professionals.
抗生素耐药性是当今一个关键问题，因此需要监测各个部门的抗生素使用情况。为了确定全球范围内牙医开具的抗生素限定日剂量（DDD），我们在PubMed、ProQuest、ScienceDirect、Web of Science、Scopus和EBSCOhost数据库中进行了全面检索，最终在本范围综述中纳入了15份文献。研究国家中牙医开具的口服抗生素每1000居民每日限定日剂量（DID）一般低于2.11，但韩国除外，其每1000患者每日限定日剂量（DPD）低于6.97。除克罗地亚和比利时外，大多数国家在新冠疫情大流行之前DID呈下降趋势，但疫情期间的限制措施导致这些数字有所增加。在大多数国家，青霉素类抗生素是牙医最常开具的抗生素。本研究凸显了全球范围内牙医开具抗生素方面存在的重大差距和缺失数据。然而，这也表明发布指南、开展教育以及对抗生素使用进行评估能够促使牙科专业人员开出更可控、更恰当的处方。
