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牙科抗菌药物管理:开发一款用于合理抗生素处方以应对误诊的移动应用程序。

Dental Antimicrobial Stewardship: Developing a Mobile Application for Rational Antibiotic Prescribing to Tackle Misdiagnosis.

作者信息

Roganović Jelena, Djordjević Stefan, Barać Milena, Crnjanski Jasna, Milanović Ivana, Ilić Jugoslav

机构信息

Department of Pharmacology in Dentistry, Faculty of Dental Medicine, University of Belgrade, 11000 Belgrade, Serbia.

IMP-Computer Systems Ltd. (IMP-CS), Institute Mihajlo Pupin, 11000 Belgrade, Serbia.

出版信息

Antibiotics (Basel). 2024 Nov 26;13(12):1135. doi: 10.3390/antibiotics13121135.

DOI:10.3390/antibiotics13121135
PMID:39766525
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11672394/
Abstract

BACKGROUND/OBJECTIVES: Inexperienced dentists and dental students are especially prone to misdiagnosis, and this represents a huge problem regarding antimicrobial stewardship. We aimed to develop a mobile app for rational antibiotic prescribing in dentistry based on local-systemic symptoms and patient factors, rather than solely on diagnosis, to tackle misdiagnosis.

METHODS

The study involved 64 participants, 50 of which were third-year dental students attending a pharmacology course focusing on antimicrobials, comprising lectures and practical sessions without (noAPP group, n = 22) or with (APP group n = 28) the assistance of a mobile application. The other 14 participants were practicing dentists who decided to register and use the application. All registered users of the application were asked to take a feedback survey, while learning outcomes were evaluated via a pharmacology quiz.

RESULTS

A decision tree was used for application development. In total, 76 impressions were collected on the application. The majority of the impressions were related to odontogenic-endodontic infections. Multiple linear regression analysis did not reveal differences in survey responses between practicing dentists and undergraduate students in the feedback survey responses. There was a significant difference in the mean pharmacology test scores between the noAPP and APP groups (5.50 ± 1.80 vs. 7.21 ± 1.03, = 0.0001).

CONCLUSIONS

The dentalantibiotic.com application was developed to support rational antibiotic prescribing, in view of tackling misdiagnosis, among inexperienced dentists, as well as to assist in undergraduates' pharmacology learning, and the current study shows its large impact as an educational tool. The majority of participants considered it easy to use, efficient in facilitating the right antibiotic choice, and useful for everyday decision-making.

摘要

背景/目的:经验不足的牙医和牙科学生特别容易出现误诊,这在抗菌药物管理方面是一个巨大的问题。我们旨在开发一款基于局部-全身症状和患者因素而非单纯基于诊断的牙科合理抗生素处方移动应用程序,以解决误诊问题。

方法

该研究涉及64名参与者,其中50名是参加专注于抗菌药物的药理学课程的三年级牙科学生,课程包括讲座和实践课程,分为无移动应用程序辅助组(无应用程序组,n = 22)和有移动应用程序辅助组(应用程序组,n = 28)。另外14名参与者是决定注册并使用该应用程序的执业牙医。所有应用程序的注册用户都被要求进行反馈调查,同时通过药理学测验评估学习成果。

结果

使用决策树进行应用程序开发。总共收集了76条关于该应用程序的意见。大多数意见与牙源性牙髓感染有关。多元线性回归分析未发现执业牙医和本科生在反馈调查回复中的差异。无应用程序组和应用程序组的平均药理学测试成绩存在显著差异(5.50 ± 1.80对7.21 ± 1.03,P = 0.0001)。

结论

开发dentalantibiotic.com应用程序是为了支持合理抗生素处方,鉴于解决经验不足的牙医中的误诊问题,以及协助本科生的药理学学习,当前研究表明其作为一种教育工具具有很大影响。大多数参与者认为它易于使用,在促进正确的抗生素选择方面高效,并且对日常决策有用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c126/11672394/5d3aad100a88/antibiotics-13-01135-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c126/11672394/5c4cda3c9426/antibiotics-13-01135-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c126/11672394/5d3aad100a88/antibiotics-13-01135-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c126/11672394/5c4cda3c9426/antibiotics-13-01135-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c126/11672394/5d3aad100a88/antibiotics-13-01135-g002.jpg

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