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高盐饮食与肠道微生物群:对心血管疾病和炎症性肠病的影响

High-Salt Diet and Intestinal Microbiota: Influence on Cardiovascular Disease and Inflammatory Bowel Disease.

作者信息

Wang Xueyang, Lang Fuyuan, Liu Dan

机构信息

Queen Mary College, Nanchang University, Xuefu Road, Nanchang 330001, China.

School of Pharmacy, Jiangxi Medical College, Nanchang University, Nanchang 330006, China.

出版信息

Biology (Basel). 2024 Aug 29;13(9):674. doi: 10.3390/biology13090674.

Abstract

Salt, or sodium chloride, is an essential component of the human diet. Recent studies have demonstrated that dietary patterns characterized by a high intake of salt can influence the abundance and diversity of the gut microbiota, and may play a pivotal role in the etiology and exacerbation of certain diseases, including inflammatory bowel disease and cardiovascular disease. The objective of this review is to synthesize the effects of elevated salt consumption on the gut microbiota, including its influence on gut microbial metabolites and the gut immune system. Additionally, this review will investigate the potential implications of these effects for the development of cardiovascular disease and inflammatory bowel disease. The findings of this study offer novel insights and avenues for the management of two common conditions with significant clinical implications.

摘要

盐,即氯化钠,是人类饮食的重要组成部分。最近的研究表明,以高盐摄入为特征的饮食模式会影响肠道微生物群的丰度和多样性,并可能在某些疾病(包括炎症性肠病和心血管疾病)的病因和病情加重中起关键作用。本综述的目的是综合高盐饮食对肠道微生物群的影响,包括其对肠道微生物代谢产物和肠道免疫系统的影响。此外,本综述将探讨这些影响对心血管疾病和炎症性肠病发展的潜在影响。这项研究的结果为管理这两种具有重大临床意义的常见病症提供了新的见解和途径。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8275/11429420/a4204d55d5fb/biology-13-00674-g001.jpg

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