Department of Functional Sciences, 'Victor Babes' University of Medicine and Pharmacy Timisoara, Eftimie Murgu Square No. 2, 300041 Timisoara, Romania.
Center for Translational Research and Systems Medicine, 'Victor Babes' University of Medicine and Pharmacy Timisoara, Eftimie Murgu Square No. 2, 300041 Timisoara, Romania.
Medicina (Kaunas). 2024 Sep 1;60(9):1430. doi: 10.3390/medicina60091430.
: This study investigates the relationship between thyroid eye disease (TED) and open-angle glaucoma (OAG), focusing on disease severity and clinical features. : Conducted at the Timis County Emergency Clinical Hospital, the research included 106 patients, with 53 having both conditions and 53 having only OAG. Key metrics analyzed included intraocular pressure (IOP) using a Goldmann applanation tonometer, the retinal nerve fiber layer (RNFL) thickness, and optic nerve head (ONH) characteristics evaluated using optical coherence tomography (OCT). : Results indicated that patients with both TED and OAG experienced a 6.09% reduction in RNFL thickness and showed more rapid disease progression, with 48.35% having active TED. The mean IOP in TED patients was 27.5 ± 4.9 mmHg, which was similar to those with only OAG. Demographic factors, including age and gender, influenced the clinical course and disease severity. : These findings underscore the importance of specialized monitoring and treatment strategies for patients with coexisting TED and OAG to prevent vision loss.
这项研究调查了甲状腺眼病（TED）和开角型青光眼（OAG）之间的关系，重点关注疾病的严重程度和临床特征。该研究在蒂米什县紧急临床医院进行，共纳入了 106 名患者，其中 53 名同时患有这两种疾病，53 名仅患有 OAG。分析的关键指标包括使用 Goldmann 压平眼压计测量的眼内压（IOP）、视网膜神经纤维层（RNFL）厚度以及使用光学相干断层扫描（OCT）评估的视神经头（ONH）特征。结果表明，同时患有 TED 和 OAG 的患者的 RNFL 厚度减少了 6.09%，疾病进展更快，其中 48.35%的患者患有活动性 TED。TED 患者的平均眼压为 27.5±4.9mmHg，与仅患有 OAG 的患者相似。年龄和性别等人口统计学因素影响疾病的临床过程和严重程度。这些发现强调了对同时患有 TED 和 OAG 的患者进行专门监测和治疗策略的重要性，以防止视力丧失。
