Suppr超能文献

虚弱与哮喘的关联。

Association between Frailty and Asthma.

机构信息

Department of Thoracic and Cardiovascular Surgery, Pusan National University School of Medicine, Busan 49241, Republic of Korea.

Department of Thoracic and Cardiovascular Surgery, Pusan National University Yangsan Hospital, Yangsan 50612, Republic of Korea.

出版信息

Medicina (Kaunas). 2024 Sep 10;60(9):1479. doi: 10.3390/medicina60091479.

Abstract

: This study investigated whether there is an association between elderly frailty and asthma. : We examined 9745 elderly participants who did not have asthma and 275 elderly patients who had asthma diagnosed by a doctor from the 2020 Survey of Living Conditions and Welfare Needs of Korean Older Persons Survey. Study Selections: The Korean version of the fatigue, resistance, ambulation, illnesses, and loss of weight (K-FRAIL) scale was used to determine their level of frailty. The relationship between frailty and geriatric asthma was examined using multiple logistic regression analysis, which was adjusted for a number of confounding variables (socioeconomic, health behavior, psychological characteristics, and functional status). : Frailty as defined by the K-FRAIL scale was significantly higher in the asthma group (7.6%) than the non-asthma group (4.9%). The frailty phenotype component showed that resistance, ambulation, and illness severity were more severe in the asthma group than the non-asthma group. After adjusting, asthma was significantly associated with an increased risk of frailty (OR 1.45; 95% confidence interval [CI] 1.01-2.09) compared to the non-asthma group. : Frailty might be associated with elderly asthma in patients from the Korean population. Frailty may not only be associated with asthma, but also with other diseases. So, more evidence is needed to establish this association.

摘要

: 本研究旨在探讨老年人衰弱与哮喘之间是否存在关联。: 我们检查了 9745 名没有哮喘的老年人和 275 名由医生诊断为哮喘的老年人,这些老年人来自 2020 年韩国老年人生活状况和福利需求调查。研究选择:使用疲劳、抵抗力、活动能力、疾病和体重减轻(K-FRAIL)量表的韩语版本来确定他们的衰弱程度。使用多变量逻辑回归分析检查衰弱与老年哮喘之间的关系,该分析调整了许多混杂变量(社会经济、健康行为、心理特征和功能状态)。: 根据 K-FRAIL 量表,哮喘组的衰弱程度(7.6%)明显高于非哮喘组(4.9%)。衰弱表型成分表明,与非哮喘组相比,哮喘组的抵抗力、活动能力和疾病严重程度更严重。调整后,与非哮喘组相比,哮喘与衰弱风险增加显著相关(OR 1.45;95%置信区间 [CI] 1.01-2.09)。: 在韩国人群中,衰弱可能与老年哮喘有关。衰弱不仅与哮喘有关,还可能与其他疾病有关。因此,需要更多的证据来建立这种关联。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/285a/11434337/679feea8cd01/medicina-60-01479-g001.jpg

相似文献

1
Association between Frailty and Asthma.
Medicina (Kaunas). 2024 Sep 10;60(9):1479. doi: 10.3390/medicina60091479.
2
Association between frailty and cognitive status among ambulating Korean elderly: An observational study.
Medicine (Baltimore). 2024 Aug 9;103(32):e39222. doi: 10.1097/MD.0000000000039222.
3
Clinical Frailty Scale, K-FRAIL questionnaire, and clinical outcomes in an acute hospitalist unit in Korea.
Korean J Intern Med. 2021 Sep;36(5):1233-1241. doi: 10.3904/kjim.2020.677. Epub 2021 Jun 4.
4
Frailty and Risk of Adverse Outcomes in Hospitalized Older Adults: A Comparison of Different Frailty Measures.
J Am Med Dir Assoc. 2017 Jul 1;18(7):638.e7-638.e11. doi: 10.1016/j.jamda.2017.04.011. Epub 2017 Jun 3.
5
Longitudinal association between eating alone and deterioration in frailty status: The Korean Frailty and Aging Cohort Study.
Exp Gerontol. 2023 Feb;172:112078. doi: 10.1016/j.exger.2022.112078. Epub 2022 Dec 28.
6
Association between Frailty and Albuminuria among Older Chinese Inpatients.
J Nutr Health Aging. 2021;25(2):197-200. doi: 10.1007/s12603-020-1481-6.
7
The Korean version of the FRAIL scale: clinical feasibility and validity of assessing the frailty status of Korean elderly.
Korean J Intern Med. 2016 May;31(3):594-600. doi: 10.3904/kjim.2014.331. Epub 2015 Dec 23.
8
Higher free thyroxine levels are associated with frailty in older men: the Health In Men Study.
Clin Endocrinol (Oxf). 2012 May;76(5):741-8. doi: 10.1111/j.1365-2265.2011.04290.x.

引用本文的文献

2
Association Between Life's Essential 8 and Frailty in Adults with Asthma.
Dose Response. 2025 May 27;23(2):15593258251342829. doi: 10.1177/15593258251342829. eCollection 2025 Apr-Jun.

本文引用的文献

1
The causal relationship between risk of developing bronchial asthma and frailty: a bidirectional two-sample Mendelian randomization study.
Front Med (Lausanne). 2023 Dec 15;10:1289026. doi: 10.3389/fmed.2023.1289026. eCollection 2023.
3
Handgrip strength as a diagnostic tool for frailty risk in elderly patients with moderate to severe asthma.
J Bras Pneumol. 2023 Jul 24;49(3):e20220465. doi: 10.36416/1806-3756/e20220465. eCollection 2023.
4
Geriatrics Fact Sheet in Korea 2021.
Ann Geriatr Med Res. 2021 Jun;25(2):65-71. doi: 10.4235/agmr.21.0063. Epub 2021 Jun 29.
5
Are frailty and patient-reported outcomes independent in subjects with asthma? A cross-sectional observational study.
Clin Respir J. 2021 Feb;15(2):216-224. doi: 10.1111/crj.13287. Epub 2020 Dec 9.
6
Asthma is associated with frailty among community-dwelling adults: the GAZEL cohort.
BMJ Open Respir Res. 2020 Feb;7(1). doi: 10.1136/bmjresp-2019-000526.
7
Frailty assessment in older adults with chronic obstructive respiratory diseases.
Clin Interv Aging. 2018 Aug 29;13:1513-1524. doi: 10.2147/CIA.S173239. eCollection 2018.
8
The Relationship Between COPD and Frailty: A Systematic Review and Meta-Analysis of Observational Studies.
Chest. 2018 Jul;154(1):21-40. doi: 10.1016/j.chest.2018.02.014. Epub 2018 Mar 1.
9
Physical activity in chronic obstructive pulmonary disease: clinical impact and risk factors.
Korean J Intern Med. 2018 Jan;33(1):75-77. doi: 10.3904/kjim.2017.387. Epub 2017 Dec 28.

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验