Department of Geriatrics, Sheng Jing Hospital, China Medical University, Shenyang, People's Republic of China,
Clin Interv Aging. 2018 Aug 29;13:1513-1524. doi: 10.2147/CIA.S173239. eCollection 2018.
The number of patients with chronic obstructive pulmonary disease (COPD) has been rising with continued exposure to environmental risk factors and aging of populations around the world. Frailty is a geriatric syndrome with a decline in physiological reserve and often coexists with chronic diseases such as COPD. Frailty is an independent risk factor for the development and progression of COPD, and COPD can lead to frailty; treating one might improve the other. Thus, there is an increasing interest in the assessment of frailty in patients with COPD. Furthermore, early identification and assessment of frailty in patients with COPD may affect the choice of intervention and improve its effectiveness. Based on the current literature, the intent of this review was to summarize and discuss frailty assessment tools used for COPD patients and the relevant clinical practices for predicting outcomes. We ascertain that using suitable frailty assessment tools could facilitate physicians to screen and stratify physically frail patients with COPD. Screening appropriately targeted population can achieve better intervention outcomes and pulmonary rehabilitation among frail COPD patients.
慢性阻塞性肺疾病（COPD）患者的数量随着全球环境风险因素的持续暴露和人口老龄化而不断增加。衰弱是一种老年综合征，表现为生理储备能力下降，常与 COPD 等慢性病共存。衰弱是 COPD 发生和进展的独立危险因素，而 COPD 可导致衰弱；治疗其中一种疾病可能会改善另一种疾病。因此，人们对 COPD 患者衰弱的评估越来越感兴趣。此外，早期识别和评估 COPD 患者的衰弱状况可能会影响干预措施的选择，并提高其效果。基于目前的文献，本综述的目的是总结和讨论用于 COPD 患者的衰弱评估工具以及预测结局的相关临床实践。我们发现，使用合适的衰弱评估工具可以帮助医生筛选和分层患有 COPD 的身体虚弱的患者。对适当的目标人群进行筛查可以在衰弱的 COPD 患者中实现更好的干预结果和肺康复。
