Moreira José, Bravo Jorge, Aguiar Pedro, Delgado Bruno, Raimundo Armando, Boto Paulo
Escola Superior de Enfermagem São João de Deus, University of Évora, 7000-811 Évora, Portugal.
Comprehensive Health Research Centre (CHRC), University of Évora, 7000-849 Évora, Portugal.
J Clin Med. 2024 Sep 20;13(18):5576. doi: 10.3390/jcm13185576.
This study aimed to analyze the effect of cardiac rehabilitation programs on the health-related quality of life of patients after a coronary cardiac event using patient-reported outcome measures (PROMs) for up to 6 months of evaluation. : A comprehensive search was carried out in the MEDLINE, CINAHL, CENTRAL, and Web of Science databases for randomized controlled trials comparing the cardiac rehabilitation program with usual care. Two independent reviewers assessed the studies for inclusion, risk of bias using the Cochrane tool, and quality of evidence through the GRADE system. A meta-analysis was performed on studies assessing health-related quality of life with the SF-12 (Physical Component Summary and Mental Component Summary) up to 6 months after the program. : Twelve studies encompassed 2260 patients who participated in a cardiac rehabilitation program after a coronary event, with a mean age of 60.06 years. The generic PROMs used to assess quality of life were the SF-12, SF-36, EQ-5D-3L, EQ-5D-5L, and GHQ, and the specific coronary heart disease PROMs were MacNew and HeartQoL. There was a positive effect of participation in cardiac rehabilitation on the physical component of health-related quality of life at 6 months (MD [7.02]; = 0.04] and on the mental component (MD [1.06]; = 0.82) after applying the SF-12. : This study highlights the significant benefits of cardiac rehabilitation programs on health-related quality of life, particularly in the physical domain at 6 months. Assessing outcomes over time through PROMs after coronary heart events is essential, thus making it possible to personalize patients' care and improve their health status.
本研究旨在使用患者报告结局测量（PROMs）分析心脏康复计划对冠心病事件后患者健康相关生活质量的影响，评估期长达6个月。在MEDLINE、CINAHL、CENTRAL和科学网数据库中进行了全面检索，以查找比较心脏康复计划与常规护理的随机对照试验。两名独立评审员评估研究是否纳入、使用Cochrane工具评估偏倚风险以及通过GRADE系统评估证据质量。对在计划实施后长达6个月使用SF-12（身体成分总结和心理成分总结）评估健康相关生活质量的研究进行了荟萃分析。12项研究纳入了2260名冠心病事件后参加心脏康复计划的患者，平均年龄为60.06岁。用于评估生活质量的通用PROMs有SF-12、SF-36、EQ-5D-3L、EQ-5D-5L和GHQ，特定的冠心病PROMs有MacNew和HeartQoL。应用SF-12后，参与心脏康复对6个月时健康相关生活质量的身体成分有积极影响（MD [7.02]；P = 0.04），对心理成分也有积极影响（MD [1.06]；P = 0.82）。本研究强调了心脏康复计划对健康相关生活质量的显著益处，尤其是在6个月时对身体领域的益处。通过冠心病事件后的PROMs随时间评估结局至关重要，从而能够使患者护理个性化并改善其健康状况。
