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银纳米粒子提高荧光团的光稳定性:在金丝桃素研究中的应用。

Silver Nanoparticles Improve Fluorophore Photostability: Application to a Hypericin Study.

机构信息

Department of Physics and Biophysics, University of Warmia and Mazury, 10-719 Olsztyn, Poland.

出版信息

Int J Mol Sci. 2024 Sep 15;25(18):9963. doi: 10.3390/ijms25189963.

Abstract

Protection against the negative effects of solar radiation involves using cosmetics with a UV filter, but visible radiation can also have negative effects. We use dietary supplements and take medications; unfortunately, many of them contain substances that degrade under the influence of visible light, which transform into chemical compounds harmful to health. Manufacturers often include information on the prohibition of exposure to sunlight on the packaging, but consumers often do not read the product leaflet. The solution to this problem may be the addition of silver particles to preparations. In the presented article, we proposed the use of silver nanoparticles to reduce the photobleaching and photoreaction of fluorophore, while increasing the fluorescence intensity. For our research, we used a compound that is particularly sensitive to radiation: hypericin.

摘要

防护太阳辐射的负面影响包括使用带有紫外线过滤器的化妆品,但可见光辐射也可能产生负面影响。我们使用膳食补充剂和药物;不幸的是,其中许多含有在可见光影响下降解的物质,这些物质会转化为对健康有害的化合物。制造商经常在包装上注明禁止阳光照射,但消费者通常不阅读产品说明书。解决这个问题的方法可能是在制剂中添加银颗粒。在本文中,我们提出了使用纳米银颗粒来减少荧光团的光漂白和光反应,同时提高荧光强度。对于我们的研究,我们使用了一种对辐射特别敏感的化合物:金丝桃素。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2536/11432501/5525445c44ff/ijms-25-09963-g001.jpg

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