State Engineering Technology Institute for Karst Desertfication Control, School of Karst Science, Guizhou Normal University, Guiyang 550025, China.
Key Laboratory for Information System of Mountainous Areas and Protection of Ecological Environment, Guizhou Normal University, Guiyang 550025, China.
Int J Mol Sci. 2024 Sep 18;25(18):10040. doi: 10.3390/ijms251810040.
Weaning is one of the most challenging phases for piglets, and it is also the time when piglets are the most susceptible to diarrhea, which may result in significant economic losses for pig production. One of the dietary strategies for reducing post-weaning diarrhea (PWD) in piglets is to provide them with a pharmacological dose of zinc oxide (ZnO). However, excessive or long-term usage of high-dose ZnO has significant impacts on pig health and the ecological environment. Therefore, caution should be exercised when considering the use of high-dose ZnO for the prevention or treatment of PWD in piglets. In this paper, the significant role of zinc in animal health, the potential mode of action of ZnO in alleviating diarrhea, and the impact of innovative, highly efficient ZnO alternatives on the regulation of piglet diarrhea were reviewed to offer insights into the application of novel ZnO in pig production.
断奶是仔猪最具挑战性的阶段之一，也是仔猪最容易患腹泻的时候，这可能会给养猪生产带来巨大的经济损失。减少仔猪断奶后腹泻（PWD）的饮食策略之一是为仔猪提供药理剂量的氧化锌（ZnO）。然而，过量或长期使用高剂量的 ZnO 会对猪的健康和生态环境产生重大影响。因此，在考虑使用高剂量 ZnO 预防或治疗仔猪 PWD 时应谨慎。本文综述了锌在动物健康中的重要作用、ZnO 缓解腹泻的潜在作用机制，以及创新、高效 ZnO 替代品对调节仔猪腹泻的影响，以期为新型 ZnO 在养猪生产中的应用提供参考。
