Wang Jingjing, Li Chenyang, Yin Yulong, Zhang Shuo, Li Xiaozhen, Sun Qingping, Wan Dan
Department of Animal Nutrition and Feed Science, College of Animal Science and Technology, Huazhong Agricultural University, Wuhan, 430070, China.
Hunan Province Key Laboratory of Animal Nutritional Physiology and Metabolic Process, Key Laboratory of Agroecological Processes in Subtropical Region, National Engineering Laboratory for Pollution Control and Waste Utilization in Livestock and Poultry Production, Institute of Subtropical Agriculture, Chinese Academy of Sciences, Changsha, 410125, Hunan, China.
Biol Trace Elem Res. 2021 Apr;199(4):1405-1413. doi: 10.1007/s12011-020-02262-0. Epub 2020 Jun 30.
This experiment was conducted to investigate the effects of zinc oxide/zeolite on growth performance, serum biochemistry, intestinal morphology, and microflora of weaned piglets. Two hundred and fifty-six weaned piglets (Duroc × Landrace × Large) at 21 days of age were randomly assigned to 2 groups with 8 replicates and 16 piglets in each pen. The diets of high dose of zinc oxide group (HD-ZnO) supplemented with 1500 mg/kg zinc as zinc oxide, but the diet of experimental group supplemented with 500 mg/kg zinc as zinc oxide that supported on zeolite (SR-ZnO). The experiment was conducted for 2 weeks after weanling. The results showed replacement of high-dosed zinc oxide by SR-ZnO had no significant effects on growth performance and intestinal morphology. However, the dietary supplementation of SR-ZnO reduced the diarrhea rate (P < 0.05), increased the activity of serum alkaline phosphatase (ALP) (P < 0.01), and tended to reduce zinc release in stomach (P = 0.06) and increase serum total protein (TP) (P = 0.07). Although there were no significant effects in ileal microflora on α diversity, the abundance of Campylobacters was found significantly decreased (P < 0.05), whereas the abundance of Clostridium was increased (P < 0.05) after lower-dosed SR-ZnO replacement. It is revealed that replacement of HD-ZnO (1500 mg/kg) by SR-ZnO (500 mg/kg) in creep feed could improve the zinc bioavailability, regulate the intestinal flora, and alleviate the postweaning diarrhea in weaned piglets. Accordingly, the application of SR-ZnO would reduce the zinc in feed and therefore benefits for the ecological environment.
本试验旨在研究氧化锌/沸石对断奶仔猪生长性能、血清生化指标、肠道形态及微生物菌群的影响。选取256头21日龄断奶仔猪（杜洛克×长白×大白），随机分为2组，每组8个重复，每个栏舍16头仔猪。高剂量氧化锌组（HD-ZnO）日粮添加1500 mg/kg氧化锌形式的锌，而试验组日粮添加500 mg/kg氧化锌形式的锌并负载于沸石上（SR-ZnO）。断奶后试验持续2周。结果表明，用SR-ZnO替代高剂量氧化锌对生长性能和肠道形态无显著影响。然而，日粮添加SR-ZnO降低了腹泻率（P＜0.05），提高了血清碱性磷酸酶（ALP）活性（P＜0.01），并倾向于降低胃中锌的释放量（P = 0.06），提高血清总蛋白（TP）含量（P = 0.07）。虽然低剂量SR-ZnO替代后回肠微生物菌群的α多样性无显著变化，但弯曲杆菌的丰度显著降低（P＜0.05），而梭菌的丰度增加（P＜0.05）。结果表明，在开食料中用SR-ZnO（500 mg/kg）替代HD-ZnO（1500 mg/kg）可提高锌的生物利用率，调节肠道菌群，减轻断奶仔猪断奶后腹泻。因此，SR-ZnO的应用可减少饲料中的锌含量，从而有利于生态环境。
