Dykiert Irena Anna, Kraik Krzysztof, Jurczenko Lidia, Gać Paweł, Poręba Rafał, Poręba Małgorzata
Department of Physiology and Pathophysiology, Division of Pathophysiology, Wroclaw Medical University, 50-368 Wrocław, Poland.
Students' Scientific Association of Cardiovascular Diseases Prevention, Wroclaw Medical University, 50-368 Wrocław, Poland.
Life (Basel). 2024 Sep 9;14(9):1140. doi: 10.3390/life14091140.
this study aims to evaluate the prevalence of various arrhythmias and other electrocardiographic patterns within the group of individuals with overweight and obesity.
One hundred eighty-one adults (90 females and 91 males) were qualified for inclusion in the experimental group. All participants had a body mass index (BMI) exceeding 25 kg/m (98 patients with obesity and 83 with overweight). The mean BMI in the obesity group was 33.6 kg/m, and all participants had class 1 obesity. The control group comprised 69 individuals (56 females and 13 males) with normal BMI. The basic measurements were performed, and the participants filled out questionnaires describing their health conditions and lifestyles. Each participant underwent an electrocardiographic (ECG) examination and a 24 h Holter ECG examination.
In patients with class 1 obesity compared to the control patients, the average numbers of premature ventricular beats (PVBs) and premature supraventricular beats (SPBs) were statistically significantly higher ( 0.030 and 0.042). There was a positive correlation between body weight and PVB ( 0.028) and between body weight and SPB ( 0.028). Moreover, BMI and waist circumference were correlated with SPB ( 0.043 and 0.031). In the backward stepwise multivariate regression model considering 24 h Holter ECG monitoring, concerning SPB as the dependent variable, it was observed that BMI (especially obesity class 1), type 2 diabetes, and thyroid disease exhibited the highest regression coefficients.
obesity, even in class 1, might be a factor in a more frequent occurrence of abnormalities in electrocardiographic tests.
本研究旨在评估超重和肥胖个体群体中各种心律失常及其他心电图模式的患病率。
181名成年人（90名女性和91名男性）符合纳入实验组的条件。所有参与者的体重指数（BMI）均超过25kg/m²（98例肥胖患者和83例超重患者）。肥胖组的平均BMI为33.6kg/m²，所有参与者均为1级肥胖。对照组由69名BMI正常的个体组成（56名女性和13名男性）。进行了基本测量，参与者填写了描述其健康状况和生活方式的问卷。每位参与者均接受了心电图（ECG）检查和24小时动态心电图检查。
与对照组患者相比，1级肥胖患者的室性早搏（PVB）和室上性早搏（SPB）的平均数量在统计学上显著更高（分别为0.030和0.042）。体重与PVB之间存在正相关（r = 0.028），体重与SPB之间也存在正相关（r = 0.028）。此外，BMI和腰围与SPB相关（r分别为0.043和0.031）。在考虑24小时动态心电图监测的向后逐步多元回归模型中，以SPB作为因变量，观察到BMI（尤其是1级肥胖）、2型糖尿病和甲状腺疾病表现出最高的回归系数。
即使是1级肥胖，也可能是心电图检查中异常更频繁发生的一个因素。
