Stephan Brigitte, Meineke Anna, Augustin Matthias, Sorbe Christina
Institute for Health Services Research in Dermatology and Nursing (IVDP), University Medical Center Hamburg-Eppendorf (UKE), 20251 Hamburg, Germany.
Life (Basel). 2024 Sep 12;14(9):1157. doi: 10.3390/life14091157.
The national guidelines and the Standing Committee on Vaccination (STIKO) of the Robert Koch Institute (RKI) in Germany support preventive vaccinations for patients under immunomodulatory treatments.
Retrospective analysis of data from patients with chronic inflammatory skin diseases from December 2021 to December 2022 with a focus on preventive vaccinations against influenza virus, varicella zoster virus, or SARS-CoV-2.
Patients with chronic inflammatory skin diseases were referred to our university outpatient's clinic for recommendations of systemic therapy. Vaccinations against influenza virus, varicella zoster virus, or SARS-CoV-2 were documented in 7365 analyzed patient files. A total of 79.7% were completely vaccinated against SARS-CoV-2, 49.7% patients were vaccinated against the influenza virus, and only 9.2% were completely vaccinated against varicella zoster virus.
In our patients who came for counselling before or during systemic treatment, vaccination rates against SARS-CoV-2, varicella zoster virus, or influenza virus were low. Patients age 60 and above had higher rates than the average German population of the same age, but still no satisfying protection.
We suggest informing patients about preventive vaccination before and during systemic immunomodulatory treatments and emphasize the need for active communication in this vulnerable patient group.
德国国家指南以及罗伯特·科赫研究所（RKI）的疫苗接种常务委员会（STIKO）支持对接受免疫调节治疗的患者进行预防性疫苗接种。
对2021年12月至2022年12月患有慢性炎症性皮肤病患者的数据进行回顾性分析，重点关注针对流感病毒、水痘带状疱疹病毒或严重急性呼吸综合征冠状病毒2（SARS-CoV-2）的预防性疫苗接种。
患有慢性炎症性皮肤病的患者被转诊至我校门诊以获取全身治疗的建议。在7365份分析的患者档案中记录了针对流感病毒、水痘带状疱疹病毒或SARS-CoV-2的疫苗接种情况。共有79.7%的患者完成了SARS-CoV-2疫苗接种，49.7%的患者接种了流感病毒疫苗，而仅9.2%的患者完成了水痘带状疱疹病毒疫苗接种。
在我们那些在全身治疗前或治疗期间前来咨询的患者中，针对SARS-CoV-2、水痘带状疱疹病毒或流感病毒的疫苗接种率较低。60岁及以上的患者接种率高于同龄德国人的平均水平，但仍未提供令人满意的保护。
我们建议在全身免疫调节治疗前和治疗期间告知患者预防性疫苗接种事宜，并强调在这一脆弱患者群体中进行积极沟通的必要性。
