干酪乳杆菌对同基因小鼠和豚鼠Lewis肺癌及10号线肝癌的抗肿瘤活性。
Anti-tumour activity of Lactobacillus casei on Lewis lung carcinoma and line-10 hepatoma in syngeneic mice and guinea pigs.
作者信息
Matsuzaki T, Yokokura T, Azuma I
出版信息
Cancer Immunol Immunother. 1985;20(1):18-22. doi: 10.1007/BF00199768.
Abstract
The anti-tumour activity of Lactobacillus casei YIT 9018 (LC 9018) on Lewis lung carcinoma (3LL) in C57BL/6 mice and line-10 hepatoma in strain-2 guinea pigs was examined. Intravenous injection of LC 9018 was effective for inhibition of pulmonary metastases in C57BL/6 mice after s.c. inoculation with 3LL tumours. Intralesional (i.l.) injection of LC 9018 was also effective for both prolongation of the survival period and inhibition of pulmonary metastases in 3LL tumour-bearing mice. The combination treatment of i.l. and i.v. injections of LC 9018 before or after surgical excision of the primary tumour remarkably inhibited the pulmonary metastases after inoculation with 3LL tumour. Intralesional injection of LC 9018 was effective for regression of the established tumours of line-10 hepatoma inoculated i.d. and for induction of systemic tumour immunity in strain-2 guinea pigs.
摘要
研究了干酪乳杆菌YIT 9018（LC 9018）对C57BL/6小鼠Lewis肺癌（3LL）和2系豚鼠10号线肝癌的抗肿瘤活性。在皮下接种3LL肿瘤后，静脉注射LC 9018对抑制C57BL/6小鼠的肺转移有效。瘤内注射LC 9018对延长3LL荷瘤小鼠的生存期和抑制肺转移也有效。在原发性肿瘤手术切除之前或之后，瘤内和静脉注射LC 9018的联合治疗显著抑制了接种3LL肿瘤后的肺转移。瘤内注射LC 9018对接种于皮内的10号线肝癌的已建立肿瘤的消退以及对2系豚鼠的全身肿瘤免疫诱导有效。
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本文引用的文献
1
2
Definitive evidence that natural killer (NK) cells inhibit experimental tumor metastases in vivo.自然杀伤（NK）细胞在体内抑制实验性肿瘤转移的确凿证据。
J Immunol. 1981 Nov;127(5):1754-8.
3
4
Role of NK cells in the control of metastatic spread and growth of tumor cells in mice.自然杀伤细胞在控制小鼠肿瘤细胞转移扩散和生长中的作用。
Int J Cancer. 1982 Jul 15;30(1):107-12. doi: 10.1002/ijc.2910300118.
5
Role of Corynebacterium parvum in the activation of peritoneal macrophages. 1. Association between intracellular C. parvum and cytotoxic macrophages.短小棒状杆菌在腹膜巨噬细胞激活中的作用。1. 细胞内短小棒状杆菌与细胞毒性巨噬细胞之间的关联。
Cell Immunol. 1982 Jun;70(1):65-75. doi: 10.1016/0008-8749(82)90133-2.
6
Control of lung metastasis progression in mice: role of growth kinetics of 3LL Lewis lung carcinoma and host immune reactivity.小鼠肺转移进展的控制：3LL Lewis肺癌生长动力学和宿主免疫反应性的作用。
J Natl Cancer Inst. 1980 Dec;65(6):1257-64.
7
Role of natural killer cells in the destruction of circulating tumor emboli.自然杀伤细胞在循环肿瘤栓子破坏中的作用。
J Natl Cancer Inst. 1980 Oct;65(4):801-9. doi: 10.1093/jnci/65.4.801.
8
Randomly controlled study of chemotherapy versus chemoimmunotherapy in postoperative gastric cancer patients.
Cancer Res. 1983 Jun;43(6):3001-7.
9
Antitumor activity of Lactobacillus casei in mice.干酪乳杆菌在小鼠体内的抗肿瘤活性。
Gan. 1981 Aug;72(4):517-23.
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