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Blood-brain barrier-penetrating single CRISPR-Cas9 nanocapsules for effective and safe glioblastoma gene therapy.血脑屏障穿透型单 CRISPR-Cas9 纳米胶囊用于胶质母细胞瘤的有效和安全基因治疗。
Sci Adv. 2022 Apr 22;8(16):eabm8011. doi: 10.1126/sciadv.abm8011. Epub 2022 Apr 20.
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Stimuli-responsive chitosan as an advantageous platform for efficient delivery of bioactive agents.刺激响应性壳聚糖作为一种有效的生物活性物质传递的优势平台。
J Control Release. 2020 Jan 10;317:216-231. doi: 10.1016/j.jconrel.2019.11.029. Epub 2019 Nov 26.
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Stimulus-responsive polymeric nanogels as smart drug delivery systems.刺激响应性聚合物纳米凝胶作为智能药物传递系统。
Acta Biomater. 2019 Jul 1;92:1-18. doi: 10.1016/j.actbio.2019.05.018. Epub 2019 May 13.
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Recent advances of PLGA micro/nanoparticles for the delivery of biomacromolecular therapeutics.PLGA 微/纳米颗粒在生物大分子治疗药物传递中的最新进展。
Mater Sci Eng C Mater Biol Appl. 2018 Nov 1;92:1041-1060. doi: 10.1016/j.msec.2017.12.036. Epub 2018 Jan 5.
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3D-printing porosity: A new approach to creating elevated porosity materials and structures.3D 打印多孔性：一种创建高多孔性材料和结构的新方法。
Acta Biomater. 2018 May;72:94-109. doi: 10.1016/j.actbio.2018.03.039. Epub 2018 Mar 27.
6
Nanocomposite Hydrogels: 3D Polymer-Nanoparticle Synergies for On-Demand Drug Delivery.纳米复合水凝胶：按需药物输送的 3D 聚合物-纳米粒子协同作用。
ACS Nano. 2015 May 26;9(5):4686-97. doi: 10.1021/acsnano.5b01433. Epub 2015 May 12.
7
Dual and multi-stimuli responsive polymeric nanoparticles for programmed site-specific drug delivery.双响应和多响应型聚合物纳米粒用于靶向药物传递的程序化控制。
Biomaterials. 2013 May;34(14):3647-57. doi: 10.1016/j.biomaterials.2013.01.084. Epub 2013 Feb 14.
8
Microspheres for controlled release drug delivery.用于控释给药的微球。
Expert Opin Biol Ther. 2004 Jan;4(1):35-51. doi: 10.1517/14712598.4.1.35.

用于药物控释和缓释的聚合物递送载体的最新进展

Recent Advances in Polymeric Delivery Vehicles for Controlled and Sustained Drug Release.

作者信息

Lu Hong, Cai Zheng, Hu Ping

机构信息

Department of Burns & Plastic Surgery, Guangzhou Red Cross Hospital, Faculty of Medical Science, Jinan University, Guangzhou 510006, China.

College of Pharmacy, Jinan University, Guangzhou 510006, China.

出版信息

Pharmaceutics. 2024 Sep 7;16(9):1184. doi: 10.3390/pharmaceutics16091184.

DOI:10.3390/pharmaceutics16091184
PMID:39339220
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11435192/
Abstract

In the realm of modern therapeutics, the development of polymeric delivery vehicles has revolutionized drug administration, offering a sophisticated approach to controlled and sustained drug release [...].

摘要

在现代治疗领域，聚合物递送载体的发展彻底改变了药物给药方式，为药物的控释和缓释提供了一种先进的方法[...]。