Pekmezci Hilal, Basaran Burhan
Department of Elderly Care, Health Care Services Vocational School Recep Tayyip Erdogan University Rize Türkiye.
Department of Nutrition and Dietetics, Faculty of Health Sciences Recep Tayyip Erdogan University Rize Türkiye.
Food Sci Nutr. 2023 Nov 27;12(2):1133-1145. doi: 10.1002/fsn3.3828. eCollection 2024 Feb.
This study aimed to determine the acrylamide exposure of pregnant women resulting from the consumption of bread, coffee, and French fries and to evaluate it in terms of carcinogenic and non-carcinogenic health risks. Retrospective 24-h food consumption data of pregnant women ( = 487) was obtained using the Food Frequency Questionnaire (FFQ). Dietary acrylamide exposure was calculated according to a deterministic model, and the data were assessed by hazard index (HI) and carcinogenic risk (CR). The mean daily acrylamide exposure of pregnant women aged 18-30 and ≥31 years and in the 1st, 2nd, and 3rd trimesters was 31.4, 35.4, 38.7, 31.3, and 32.4 μg/day, respectively. The acrylamide exposure data were not significantly different among different age groups and pregnancy periods ( > .05). Dietary acrylamide exposure in pregnant women of different age groups and trimesters may cause significant and serious health problems in terms of carcinogenic risk. According to their level of contribution to average acrylamide exposure, the foods were ranked as follows: French fries> bread> coffee. There is a significant risk of cancer due to exposure to acrylamide from French fries and bread other than coffee. The findings suggest that pregnant women should avoid consuming French fries, bread, and coffee with high acrylamide levels for both their own health and their newborns' health.
本研究旨在确定孕妇因食用面包、咖啡和薯条而接触丙烯酰胺的情况，并从致癌和非致癌健康风险方面对其进行评估。通过食物频率问卷（FFQ）获取了487名孕妇的回顾性24小时食物消费数据。根据确定性模型计算膳食丙烯酰胺暴露量，并通过危害指数（HI）和致癌风险（CR）对数据进行评估。18至30岁以及≥31岁的孕妇在孕早期、孕中期和孕晚期的平均每日丙烯酰胺暴露量分别为31.4、35.4、38.7、31.3和32.4μg/天。不同年龄组和孕期的丙烯酰胺暴露数据无显著差异（P>0.05）。从致癌风险来看，不同年龄组和孕期的孕妇膳食丙烯酰胺暴露可能会导致重大且严重的健康问题。根据它们对平均丙烯酰胺暴露的贡献程度，食物的排名如下：薯条>面包>咖啡。除咖啡外，因接触薯条和面包中的丙烯酰胺存在显著的癌症风险。研究结果表明，为了自身健康和新生儿健康，孕妇应避免食用丙烯酰胺含量高的薯条、面包和咖啡。
