Department of Food Market and Consumer Research, Institute of Human Nutrition Sciences, Warsaw University of Life Sciences (WULS-SGGW), 159C Nowoursynowska Street, 02-776 Warsaw, Poland.
Cancer Epidemiology and Primary Prevention Department, Maria Sklodowska-Curie National Research Institute of Oncology, 15B Wawelska Street, 02-034 Warsaw, Poland.
Nutrients. 2024 Sep 22;16(18):3207. doi: 10.3390/nu16183207.
BACKGROUND/OBJECTIVES: The diminished quality of life experienced by cancer patients impacts not only the individuals but also the broader healthcare system. Despite the effect that cancer has on quality of life both during and after treatment, quality of life assessments are not yet commonly implemented, and the specific factors influencing quality of life are not well understood. The aim of this study was to conduct comprehensive multifactorial analysis to identify the factors that influence the quality of life in cancer patients.
This study comprised a cohort of 108 patients diagnosed with cancer. The EORTC QLQ C-30 and EORTC QLQ-INFO 25 questionnaires were used to interview participants, along with questions related to disease course and lifestyle factors.
Differences were found in various subdomains among male versus female, individuals who solicited nutritional information in cancer themselves versus those who did not, individuals who reported consulting a dietitian versus those who did not, individuals who reported a recent decrease in their food intake versus those who did not report it. The results of the stepwise multiple regression show the following factors as the most important factors affecting their quality of life: patients soliciting nutritional information, reduced food intake, types of nutrition support, age, gender, seeking consultation with a dietitian, place of residence, and education level.
In addition to sociodemographic variables and those related to the location, course, and treatment of cancer, including type of cancer, the variable related to patients' declared need for soliciting nutritional information and seeking consultation with a dietitian may also influence quality of life. Therefore, the above factors in determining the quality of life and well-being of patients should also be considered in a holistic approach to patient care.
背景/目的：癌症患者生活质量的下降不仅影响个人，还影响整个医疗保健系统。尽管癌症在治疗期间和治疗后都会对生活质量产生影响，但目前尚未普遍进行生活质量评估，并且生活质量的具体影响因素也尚未得到很好的理解。本研究旨在进行综合多因素分析，以确定影响癌症患者生活质量的因素。
本研究包括 108 名被诊断患有癌症的患者。使用 EORTC QLQ C-30 和 EORTC QLQ-INFO 25 问卷对参与者进行访谈，并询问了与疾病过程和生活方式因素相关的问题。
在男性与女性、主动寻求癌症营养信息的患者与未主动寻求的患者、报告咨询营养师的患者与未咨询的患者、报告近期食物摄入量减少的患者与未报告的患者之间，发现了各种亚领域的差异。逐步多元回归的结果显示，影响其生活质量的最重要因素如下：患者主动寻求营养信息、食物摄入量减少、营养支持类型、年龄、性别、寻求营养师咨询、居住地和教育水平。
除了社会人口统计学变量以及与癌症的位置、病程和治疗相关的变量（包括癌症类型）外，与患者声明寻求营养信息和寻求营养师咨询的需求相关的变量也可能影响生活质量。因此，在整体患者护理中，也应考虑这些因素在确定患者生活质量和幸福感方面的作用。
