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基于功能化离子液体的高灵敏荧光探针用于及时检测食品中痕量 Hg 和 CHHg。

A highly sensitive fluorescent probe based on functionalised ionic liquids for timely detection of trace Hg and CHHg in food.

机构信息

College of Chemical Engineering, Zhejiang University of Technology, Hangzhou 310014, People's Republic of China.

College of Pharmacy, South-Central University for Nationalities, Wuhan 430074, China.

出版信息

Food Chem. 2025 Jan 15;463(Pt 3):141343. doi: 10.1016/j.foodchem.2024.141343. Epub 2024 Sep 18.

Abstract

A novel fluorescent probe was fabricated using fluorescein-based ionic liquids (ILs) to effectively achieve rapid and accurate detection of Hg and CHHg in food. A probe developed by addition of modified fluorescein into the functionalised ILs presented a promising sensitivity toward Hg and CHHg at concentrations of 0.4 and 60 nM, respectively. In addition, the novel probe could achieve visual and timely detection of Hg and CHHg by the naked eyes at concentrations of 0.1 and 1 μM, respectively. The probe could also overcome the interference of potential ions and common organic ligands and detect Hg and CHHg in real food samples, such as green tea and liquor. The probe could be converted into a paper-based sensor to visually detect Hg and CHHg at levels as low as 10 nM.

摘要

一种新型荧光探针采用基于荧光素的离子液体(ILs)制备,可有效实现对食品中 Hg 和 CHHg 的快速准确检测。通过将修饰后的荧光素添加到功能化 ILs 中开发的探针对 Hg 和 CHHg 的浓度分别为 0.4 和 60 nM 时表现出很高的灵敏度。此外,新型探针可以通过肉眼在 0.1 和 1 μM 的浓度下实现对 Hg 和 CHHg 的可视化和实时检测。该探针还可以克服潜在离子和常见有机配体的干扰,并检测实际食品样品(如绿茶和酒)中的 Hg 和 CHHg。该探针可转换为纸质传感器,以在低至 10 nM 的水平下可视化检测 Hg 和 CHHg。

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