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影响 42 个低收入和中等收入国家首剂麻疹疫苗接种率的因素。

Factors influencing the first dose of measles vaccination uptake in 42 low- and middle-income countries.

机构信息

Statistics Discipline, Science, Engineering and Technology School, Khulna University, Khulna, 9208, Bangladesh.

Statistics Discipline, Science, Engineering and Technology School, Khulna University, Khulna, 9208, Bangladesh.

出版信息

Public Health. 2024 Dec;237:85-93. doi: 10.1016/j.puhe.2024.09.017. Epub 2024 Sep 27.

Abstract

OBJECTIVES

Vaccination against measles still stands as a highly impactful public health strategy for mitigating childhood morbidity and mortality. Relatively poor immunization coverage among children has been observed in low and middle-income countries (LMICs). Our study intended to determine socio-demographic factors associated with the 1st dose of measles vaccination among South Asian (SA) and SubSaharan African (SSA) countries children.

STUDY DESIGN

This was a cross-sectional study.

METHODS

This study utilized demographic and health survey data from 42 low-and middle-income countries (LMICs) in SA and SSA. The children's dataset yielded 255,775 children between the ages of 12 and 59 months. The independent predictors were determined by using crude and adjusted odds ratios with 95% confidence intervals (CI).

RESULTS

The prevalence of first-dose measles-immunized children was 55.5% for the selected LMICs. The multivariable analysis for combined regions (SA and SSA) showed that parents with a higher level of education, rich wealth quintile, mothers with media access, mothers with more than four antenatal care (ANC) visits and baby postnatal check-up (PNC) within two months were significantly associated with the first dose of measles vaccination among children.

CONCLUSION

The first dose measles immunization coverage in the selected LMICs was considerably low. To boost the uptake of childhood measles vaccination, public health interventions particularly need to focus on children born to uneducated parents, poor families, and those who have not used health services (ANC and PNC). Financial funding is crucial for establishing mobile vaccination clinics to improve immunization rates among the impoverished.

摘要

目的

麻疹疫苗接种仍然是减轻儿童发病率和死亡率的极具影响力的公共卫生策略。在中低收入国家(LMICs),儿童的免疫接种覆盖率相对较低。我们的研究旨在确定与南亚(SA)和撒哈拉以南非洲(SSA)国家儿童的麻疹疫苗第一剂相关的社会人口因素。

研究设计

这是一项横断面研究。

方法

本研究利用来自 SA 和 SSA 的 42 个中低收入国家(LMICs)的人口与健康调查数据。儿童数据集包含了 12 至 59 个月大的 255775 名儿童。使用粗比值比和调整后的比值比及其 95%置信区间(CI)确定了独立预测因素。

结果

所选 LMICs 的第一剂麻疹免疫儿童的流行率为 55.5%。对合并地区(SA 和 SSA)的多变量分析表明,父母受教育程度较高、富裕程度较高、母亲有媒体接触、母亲接受超过四次产前护理(ANC)和两个月内新生儿检查(PNC)与儿童的第一剂麻疹疫苗接种显著相关。

结论

所选 LMICs 的第一剂麻疹免疫覆盖率相当低。为了提高儿童麻疹疫苗接种率,公共卫生干预措施特别需要关注未受过教育的父母、贫困家庭和未使用卫生服务(ANC 和 PNC)的儿童。建立流动疫苗接种诊所需要资金,以提高贫困人口的免疫接种率。

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