迈向可操作的抑郁症风险神经标志物？
Toward actionable neural markers of depression risk?
机构信息
Center for Depression, Anxiety and Stress Research, McLean Hospital, Belmont, MA, USA; McLean Imaging Center, McLean Hospital, Belmont, MA, USA; Harvard Medical School, Department of Psychiatry, Boston, MA, USA.
出版信息
Trends Neurosci. 2024 Nov;47(11):851-852. doi: 10.1016/j.tins.2024.09.007. Epub 2024 Sep 27.
Abstract
The search for neural markers of depression remains challenging. Despite progress, neuroimaging results have generally not yielded actionable findings that could transform how we understand and treat this disorder. However, in a recent study, Lynch and colleagues identified enlargement of the frontrostriatal salience network as a reproducible, trait-like marker of depression.
摘要
寻找抑郁症的神经标志物仍然具有挑战性。尽管取得了进展，但神经影像学的结果通常没有产生可采取的发现，这些发现可以改变我们对这种疾病的理解和治疗方式。然而，在最近的一项研究中，Lynch 及其同事发现，前脑纹状体突显网络的扩大是抑郁症的一种可重复的、特质性的标志物。
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