抗谷氨酸抗体可降低老年记忆障碍小鼠脑结构中的白细胞介素 6 含量。
Antibodies to Glutamate Reduce the IL-6 Content in Cerebral Structures in Mice with Age-Related Memory Impairment.
机构信息
Institute of General Pathology and Pathophysiology, Moscow, Russia.
出版信息
Bull Exp Biol Med. 2024 Sep;177(5):607-609. doi: 10.1007/s10517-024-06233-6. Epub 2024 Sep 28.
PMID:39342009
Abstract
Intranasal administration of antibodies to glutamate for 14 days improved passive avoidance conditioning and reduces the content of IL-6 within 7 days after their withdrawal in the prefrontal cortex and hippocampus of aging C57BL/6 mice.
摘要
鼻腔内给予谷氨酸抗体 14 天可改善衰老 C57BL/6 小鼠前额叶皮层和海马体的被动回避条件反射，并在停药后 7 天内降低 IL-6 含量。
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