Department of Ecology, Institute of Hydrobiology, School of Life Science and Technology, Key Laboratory of Eutrophication and Red Tide Prevention of Guangdong Higher Education Institutes, Engineering Research Center of Tropical and Subtropical Aquatic Ecological Engineering, Ministry of Education, Jinan University, Guangzhou 510632, PR China.
Department of Ecology, Institute of Hydrobiology, School of Life Science and Technology, Key Laboratory of Eutrophication and Red Tide Prevention of Guangdong Higher Education Institutes, Engineering Research Center of Tropical and Subtropical Aquatic Ecological Engineering, Ministry of Education, Jinan University, Guangzhou 510632, PR China.
Ecotoxicol Environ Saf. 2024 Oct 15;285:117119. doi: 10.1016/j.ecoenv.2024.117119. Epub 2024 Sep 28.
Microplastics (MPs) and polychlorinated biphenyls (PCBs) are known with high persistence and toxicity, posing urgent threats to food safety and human health. However, little is known about the synergistic effect of MPs on PCBs bioaccumulation on Crassostrea hongkongensis. In the present study, diverse types of MPs were analyzed on sea water and C. hongkongensis sampled from three distinct estuary sites, and film-shaped MPs were discovered to be preferentially ingested by the oysters. Interestingly, the content of MPs and PCBs showed negative correlation (R = 0.452, p< 0.001) in the oysters sampled from site 2. Upon MPs and PCBs co-treatment, the in vivo accumulation of PCBs in C. hongkongensis was inhibited by 25.90 % when compared to the group treated with PCBs solely. PCBs stresses significantly induced the expression of genes of CYP2C31, GST, SOD and HSP70 in C. hongkongensis, while, the elevated state was compromised when co-treated with PCBs. The present research alleviates concerns about the potential effects of MPs on promoting PCBs bioaccumulation and provide a better understanding of the combined impact of MPs and PCBs on C. hongkongensis.
微塑料（MPs）和多氯联苯（PCBs）以高持久性和高毒性而闻名，对食品安全和人类健康构成了紧迫威胁。然而，对于 MPs 对香港牡蛎（Crassostrea hongkongensis）中 PCB 生物累积的协同作用知之甚少。在本研究中，对来自三个不同河口地点的海水和 C. hongkongensis 进行了多种类型的 MPs 分析，并发现薄膜状 MPs 优先被牡蛎摄入。有趣的是，在来自地点 2 的牡蛎中，MPs 和 PCBs 的含量呈负相关（R = 0.452，p<0.001）。在 MPs 和 PCBs 共同处理时，与单独用 PCBs 处理的组相比，C. hongkongensis 中 PCB 的体内积累被抑制了 25.90%。PCBs 应激显著诱导了 C. hongkongensis 中 CYP2C31、GST、SOD 和 HSP70 基因的表达，而当与 PCBs 共同处理时，这种升高状态被削弱。本研究减轻了人们对 MPs 促进 PCBs 生物累积的潜在影响的担忧，并更好地了解了 MPs 和 PCBs 对 C. hongkongensis 的综合影响。
