Department of Rehabilitation Medicine, University of Washington, 1959 Northeast Pacific Street Box 356490, Seattle, WA 98195, USA.
Department of Neuro-Oncology, University of Texas MD Anderson Cancer Center, 1515 Holcombe Boulevard, Unit 431, Houston, TX 77030, USA.
Neurol Clin. 2024 Nov;42(4):875-887. doi: 10.1016/j.ncl.2024.05.012. Epub 2024 Jun 15.
Cognitive dysfunction is common in cancers and their treatments. Factors that can contribute to cognitive dysfunction include direct and indirect effects of cancer, surgery, radiation, systemic therapy, as well as comorbidities, fatigue, and mood disturbance. Using objective, validated measures, a neuropsychological evaluation can provide information regarding patterns of cognitive function. Emphasis of cognitive domains assessed may vary depending on disease and treatment history. Cognitive interventions can minimize the effects of cancer-related cognitive dysfunction on daily life.
认知功能障碍在癌症及其治疗中很常见。导致认知功能障碍的因素包括癌症本身及其治疗(直接影响)、手术、放疗、全身治疗以及合并症、疲劳和情绪障碍(间接影响)等。神经心理评估采用客观、有效的测量方法,可以提供认知功能模式的相关信息。评估的认知领域重点可能因疾病和治疗史而异。认知干预可以最大限度地减少癌症相关认知功能障碍对日常生活的影响。