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甲状腺细针抽吸标本充足性:穿刺针的非劣效性研究和成本效益比较。

Thyroid fine needle aspiration specimen adequacy: a noninferiority study and cost-effectiveness comparison of puncture needles.

机构信息

Department of General Surgery, Fuyang People's Hospital, 501 Sanqing Road, Fuyang, 236000, China.

出版信息

Sci Rep. 2024 Sep 29;14(1):22554. doi: 10.1038/s41598-024-74209-7.

DOI:10.1038/s41598-024-74209-7
PMID:39343786
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11439899/
Abstract

Needle selection plays a pivotal role in determining the success of fine needle aspiration (FNA) procedures. Two commonly utilized puncture needles for thyroid FNA are the conventional syringe needle and the stylet needle. Syringe needles are known for their cost-effectiveness in comparison to stylet needles. This study aimed to determine if FNA with syringe needles is non-inferior to FNA with stylet needles in terms of specimen adequacy while also comparing the direct costs associated with both needle types. A total of 220 thyroid nodules from 185 patients were prospectively included in this study. The same operator performed a total of four punctures on the same nodule twice using a syringe and a stylet needle. The results of this study show that the utilization of syringe needles for thyroid FNA was non-inferior to the use of stylet needles in terms of specimen adequacy. Cost analysis revealed that syringe needle FNA was not only less expensive (CNY 500.9 versus CNY 780) but also more effective (adequacy 85.91% versus 84.55%). In summary, given the global prevalence of FNA procedures, the economic considerations are paramount, and our findings support the routine use of syringe needles in thyroid FNA.

摘要

在决定细针吸取(FNA)程序的成功与否方面,针的选择起着关键作用。甲状腺 FNA 中常用的两种穿刺针是普通注射器针和导丝针。与导丝针相比,注射器针具有成本效益优势。本研究旨在确定与导丝针相比,注射器针在 FNA 中的标本充足性方面是否不劣于导丝针,并比较两种针类型相关的直接成本。总共前瞻性地纳入了 185 名患者的 220 个甲状腺结节。同一名操作人员在同一次结节上总共进行了 4 次穿刺,分别使用注射器和导丝针进行了两次。这项研究的结果表明,在标本充足性方面,注射器针在甲状腺 FNA 中的应用并不劣于导丝针。成本分析表明,注射器针 FNA 不仅更便宜(CNY500.9 比 CNY780),而且更有效(充足性 85.91%比 84.55%)。综上所述,鉴于 FNA 程序在全球的普遍应用,经济因素至关重要,我们的研究结果支持在甲状腺 FNA 中常规使用注射器针。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1865/11439899/b94ed12b1879/41598_2024_74209_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1865/11439899/cd72789b1851/41598_2024_74209_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1865/11439899/a0551fc0ff70/41598_2024_74209_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1865/11439899/11ea4c4f975b/41598_2024_74209_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1865/11439899/b94ed12b1879/41598_2024_74209_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1865/11439899/cd72789b1851/41598_2024_74209_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1865/11439899/a0551fc0ff70/41598_2024_74209_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1865/11439899/11ea4c4f975b/41598_2024_74209_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1865/11439899/b94ed12b1879/41598_2024_74209_Fig4_HTML.jpg

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Apropos of quality for fine-needle aspiration cytology of thyroid nodules with 22-, 23-, 25-, even 27-gauge needles and indeterminate cytology in thyroidology: an aide memory.关于使用22号、23号、25号甚至27号针进行甲状腺结节细针穿刺细胞学检查的质量以及甲状腺学中的不确定细胞学:助记法。
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