Luo Pengfei, Ma Wei, Jiao Dahai
Department of General Surgery, Fuyang People's Hospital, 501 Sanqing Road, Fuyang, 236000, China.
BMC Endocr Disord. 2025 Jun 9;25(1):145. doi: 10.1186/s12902-025-01971-8.
Compared to syringe needles, stylet needles are hypothesized to enhance the specimen adequacy of thyroid fine needle aspiration (FNA) by potentially minimizing blood contamination. However, this hypothesis lacks robust evidence for substantiation. Additionally, the substantially higher cost of stylet needles (often several orders of magnitude greater than syringe needles) raises concerns about increased procedural expenses. This study aimed to compare the outcomes of thyroid FNA using stylet versus syringe needles in a large cohort.
This retrospective analysis included 4793 FNA procedures (2088 using stylet needles and 2705 using syringe needles) performed by five operators. The primary outcome was specimen adequacy. Secondary outcomes included sensitivity, specificity, diagnostic accuracy, positive predictive value (PPV), and negative predictive value (NPV).
No significant differences were found between stylet and syringe needle FNA for specimen adequacy (85.34% vs. 87.13%), sensitivity (95.24% vs. 96.99%), specificity (78.57% vs. 78.05%), diagnostic accuracy (93.96% vs. 95.07%), PPV (98.16% vs. 97.52%), or NPV (57.89% vs. 74.42%). Performance metrics for both methods were also not significantly different within each operator's data.
This study found no significant benefit of stylet needles over syringe needles regarding specimen adequacy or diagnostic yield in thyroid FNA.
Not applicable.
与注射器针头相比，有人提出探针式针头可能通过最大限度地减少血液污染来提高甲状腺细针穿刺活检（FNA）的标本充足率。然而，这一假设缺乏有力证据支持。此外，探针式针头的成本大幅高于注射器针头（通常相差几个数量级），这引发了对手术费用增加的担忧。本研究旨在比较在一大群患者中使用探针式针头与注射器针头进行甲状腺FNA的结果。
这项回顾性分析纳入了由五名操作人员进行的4793例FNA手术（2088例使用探针式针头，2705例使用注射器针头）。主要结果是标本充足率。次要结果包括敏感性、特异性、诊断准确性、阳性预测值（PPV）和阴性预测值（NPV）。
在标本充足率（85.34%对87.13%）、敏感性（95.24%对96.99%）、特异性（78.57%对78.05%）、诊断准确性（93.96%对95.07%）、PPV（98.16%对97.52%）或NPV（57.89%对74.42%）方面，探针式针头和注射器针头FNA之间未发现显著差异。在每个操作人员的数据中，两种方法的性能指标也没有显著差异。
本研究发现，在甲状腺FNA中使用探针式针头在标本充足率或诊断率方面并不比注射器针头有显著优势。
不适用。
