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加泰罗尼亚监狱疥疮病例中应用的药理学处方和控制措施的同质性。

Homogeneity of pharmacological prescription and control measures applied in cases of scabies detected amongst inmates in Catalonia.

机构信息

Prison Infectious Diseases Group (GRUMIP). Barcelona. Spain.

Primary Healthcare Team (EAPP) Quatre Camins. La Roca del Vallés. Barcelona. Spain.

出版信息

Rev Esp Sanid Penit. 2024 May-Aug;26(2):72-76. doi: 10.18176/resp.00090.

Abstract

OBJECTIVES

To review the homogeneity of pharmacological prescription and control measures applied in cases of scabies in prisons in Catalonia.

MATERIAL AND METHOD

Observational, multicenter, and retrospective study. Cases of scabies from March 01, 2021 and March 01, 2022 were analyzed according to the International Alliance for the Control of Scabies (IACS) 2020 criteria: a) confirmed cases; b) clinically probable cases; and c) suspected cases.Epidemiological, clinical, therapeutic and regimental control variables were collected. We checked whether the interventions were homogeneous in each site. The mean and standard deviation were used as continuous variables and percentages and confidence interval (95%) for discrete variables. The Chi-square test was used to determine statistical association.

RESULTS

269 cases were detected (21.2% confirmed, 50.2% clinically probable and 28.6% suspected). 61.3% were treated with permethrin, 18.6% with ivermectin and 20.1% with both. 27.1% of the cases were withdrawn.There were no significant in-site differences in the study of contacts, isolation and treatment of clothing and belongings, but there were significant differences in the prescription of drugs (P <0.001), duration of treatment (P <0.001) and disinfection of the cell (P <0.001).

DISCUSSION

The number of detected cases is estimated to be high, and the majority (71.4%) confirmed or clinically probable. Control measures are homogeneous, except for cell disinfection, which was conventional in 59.1%. Pharmacological treatment and its duration varied between prisons. It would be advisable to establish a protocol to standardize control measures applied to new cases in the centers of Catalonia and subsequently evaluate their efficacy.

摘要

目的

回顾加泰罗尼亚监狱疥疮病例的药理学处方和控制措施的一致性。

材料和方法

观察性、多中心、回顾性研究。根据 2020 年国际疥疮控制联盟(IACS)标准,分析 2021 年 3 月 1 日至 2022 年 3 月 1 日期间的疥疮病例:a)确诊病例;b)临床疑似病例;c)疑似病例。收集流行病学、临床、治疗和监管控制变量。我们检查了每个地点的干预措施是否一致。连续变量采用平均值和标准差表示,离散变量采用百分比和置信区间(95%)表示。采用卡方检验确定统计学关联。

结果

共发现 269 例(21.2%确诊,50.2%临床疑似,28.6%疑似)。61.3%的病例用扑灭司林治疗,18.6%用伊维菌素治疗,20.1%两者并用。27.1%的病例退出。在接触者的研究、衣物和物品的隔离和治疗方面,各站点之间没有显著差异,但在药物处方(P<0.001)、治疗持续时间(P<0.001)和牢房消毒(P<0.001)方面存在显著差异。

讨论

估计检测到的病例数量较高,大多数(71.4%)为确诊或临床疑似病例。控制措施是一致的,除了 59.1%的牢房常规进行消毒。药物治疗及其持续时间在各监狱之间存在差异。建立一个方案,以规范加泰罗尼亚中心新病例的控制措施,并随后评估其疗效,将是明智的做法。

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