“水刀”止血在胃肠内镜黏膜下剥离术中的临床疗效
The clinical efficacy of "water-jet" hemostasis in gastrointestinal endoscopic submucosal dissection.
作者信息
Chen Ran, Zhang Qingyong, Hong Shiya, Chen Fengying, Huang Xiaoqing, Bao Xiongfei, Ni Zhi, Zhang Rongchun
机构信息
Department of Gastroenterology, Xiamen Humanity Hospital, Fujian Medical University, Xiamen, Fujian, P. R. China.
出版信息
Gastroenterol Rep (Oxf). 2024 Sep 26;12:goae088. doi: 10.1093/gastro/goae088. eCollection 2024.
OBJECTIVE
This study aims to evaluate the safety and efficacy of "water-jet" hemostasis during endoscopic submucosal dissection.
METHODS
In this prospective single-arm clinical study, 10 patients aged 18-60 years with gastric or intestinal mucosal lesions who were admitted to Fujian Medical University Xiamen Humanity Hospital (Xiamen, P. R. China) between June 2022 and June 2023 and met the absolute indications for endoscopic treatment were finally analyzed. The primary outcomes of this study are the incidence rates of adverse events and R0 resection, and the secondary outcomes are length of hospital stay and short- and long-term outcomes.
RESULTS
Successful hemostasis was achieved in all the included cases. In one case, the "water-jet" hemostasis failed to stop bleeding in one blood vessel, so the hemostatic forceps were used instead. No adverse events occurred in all cases. Pathologic results showed R0 resection in all samples.
CONCLUSION
The "water-jet" method is safe and feasible for hemostasis in endoscopic submucosal dissection.
目的
本研究旨在评估内镜黏膜下剥离术中“水刀”止血的安全性和有效性。
方法
在这项前瞻性单臂临床研究中，最终分析了2022年6月至2023年6月期间入住福建医科大学附属厦门弘爱医院（中国厦门）的10例年龄在18 - 60岁之间、患有胃或肠黏膜病变且符合内镜治疗绝对适应证的患者。本研究的主要结局是不良事件发生率和R0切除率，次要结局是住院时间以及短期和长期结局。
结果
所有纳入病例均成功止血。其中1例中，“水刀”止血未能止住一根血管的出血，因此改用止血钳。所有病例均未发生不良事件。病理结果显示所有样本均实现R0切除。
结论
“水刀”方法在内镜黏膜下剥离术中止血是安全可行的。
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