Renner H W
Mutat Res. 1985 Dec;144(4):251-6. doi: 10.1016/0165-7992(85)90060-0.
beta-Carotene exhibited dose-dependent anticlastogenic effects on aberrations induced by the direct-acting mutagens thio-TEPA, methyl methanesulfonate and busulfan in the in vivo chromosome aberration test (bone marrow cells, Chinese hamsters). No effect was seen when retinol was used. Apparent differences in the action of beta-carotene on aberrations induced by the three applied mutagens may be due to differences in the solubility of the compounds and to the different routes of administration.
在体内染色体畸变试验（中国仓鼠骨髓细胞）中，β-胡萝卜素对直接作用诱变剂硫代磷酸三乙酯、甲基磺酸甲酯和白消安诱导的畸变呈现剂量依赖性的抗致断裂效应。使用视黄醇时未观察到效果。β-胡萝卜素对三种应用诱变剂诱导的畸变作用存在明显差异，可能是由于化合物溶解度不同以及给药途径不同所致。
