Renner H W
Federal Research Centre for Nutrition, Karlsruhe, F.R.G.
Mutat Res. 1990 Jun;244(2):185-8. doi: 10.1016/0165-7992(90)90070-z.
The food components chlorophyllin, beta-carotene and alpha-linolenic acid (in its methyl ester form) were tested in Chinese hamsters for antimutagenic activity on the powerful mutagen thio-tepa. Each of these natural protective compounds inhibited by 70-85% the clastogenic effects induced by the mutagen. When 2 or 3 of these antimutagens were administered simultaneously no additive effects were observed. alpha-Linolenic acid methyl ester was the most effective antimutagen under the experimental conditions.
在中国仓鼠中测试了叶绿素铜钠盐、β-胡萝卜素和α-亚麻酸（甲酯形式）等食物成分对强效诱变剂硫代磷酸三乙酯的抗诱变活性。这些天然保护化合物中的每一种都能将诱变剂诱导的致断裂效应抑制70%至85%。当同时给予2种或3种这些抗诱变剂时，未观察到相加效应。在实验条件下，α-亚麻酸甲酯是最有效的抗诱变剂。
