Thongmuang Pimporn, Thongkao Kanittada, Owen Robert Wyn, Sudjaroen Yuttana
College of Allied Health Sciences, Suan Sunandha Rajabhat University, Samut Songkhram, Thailand.
Faculty of Science and Technology, Suan Sunandha Rajabhat University, Bangkok, Thailand.
J Pharm Bioallied Sci. 2024 Jul;16(Suppl 3):S2718-S2720. doi: 10.4103/jpbs.jpbs_422_24. Epub 2024 Jul 31.
Reducing the levels of oral microbials, including , , and sp., would provide the prevention of dental caries and oral illness.
To assess the antimicrobial effectiveness against oral pathogens of oral care products that contain urginea maritima extract (UM) extract, including lozenges, mouth spray, and mouthwash.
The skin irritation test was conducted on each product compared with controls in healthy participants (n = 10) by the 24-hour closed obstruction patch test. The elimination of oral pathogens in participants (n = 30) before and after product usage (as per the instruction) was assessed using a modified dip slide test.
The physical appearance and stability of oral care products were almost preferable. When added to oral care products for oral health maintenance, the cariogenic bacteria S. mutans, Candida species, and Lactobacilli species have been found to exhibit antimicrobial activity.
降低包括变形链球菌、白色念珠菌和乳杆菌属等口腔微生物的水平，可预防龋齿和口腔疾病。
评估含有海葱提取物（UM）的口腔护理产品（包括含片、口腔喷雾和漱口水）对口腔病原体的抗菌效果。
通过24小时封闭性斑贴试验，在健康参与者（n = 10）中对每种产品与对照进行皮肤刺激性试验。使用改良浸片试验评估参与者（n = 30）在产品使用前和使用后（按照说明书）口腔病原体的清除情况。
口腔护理产品的外观和稳定性几乎令人满意。当添加到用于维持口腔健康的口腔护理产品中时，已发现致龋菌变形链球菌、念珠菌属和乳杆菌属具有抗菌活性。
