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三果木、印楝和洗必泰根管冲洗剂抗菌效果的评估。

Assessment of Antimicrobial Efficacy of Triphala, Neem, and Chlorhexidine Root Canal Irrigants.

作者信息

Mohanty Saumyakanta, Nanda Soumyaranjan, Das Abhaya Chandra, Sahoo Nihar Ranjan, Sahany Subrat Kumar, Panda Saurav, Sahoo Rashmita

机构信息

Department of Conservative Dentistry and Endodontics, SCB Dental College and Hospital, Cuttack, Odisha, India.

Department of Periodontics and Oral Implantology, Institute of Dental Sciences, Siksha 'O' Anusandhan (Deemed to be University), Khandagiri Square, Bhubaneswar, Odisha, India.

出版信息

J Pharm Bioallied Sci. 2024 Jul;16(Suppl 3):S2176-S2178. doi: 10.4103/jpbs.jpbs_124_24. Epub 2024 May 13.

DOI:10.4103/jpbs.jpbs_124_24
PMID:39346266
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11426563/
Abstract

INTRODUCTION

Complete eradication of microorganisms from the root canal and three-dimensional obturation of the canal space are necessary for a successful root canal therapy. In root canal failures, is the most often detected bacterium. Microorganisms can be eliminated with the aid of chemical irrigation.

OBJECTIVES

The current research was conducted to evaluate the antimicrobial effect of triphala, neem, and chlorhexidine root canal irrigants.

MATERIALS AND METHOD

Mueller-Hinton agar plates were inoculated with the (ATCC) bacterial culture after it had been cultured overnight in brain heart infusion (BHI) broth. Agar well diffusion was used to measure antibacterial inhibition. After being introduced to their appropriate wells in agar plates, the three research irrigants were incubated for 24 hours at 37°C. Every well's bacterial inhibition zone was noted. After tabulating the results, statistical analysis was done.

RESULT

When triphala and A. indica extract (neem) were added to chlorhexidine, the highest inhibitory zone against was observed.

CONCLUSION

The herbal remedy triphala and the extract from exhibited an inhibitory zone when tested against . As a result, these irrigants might be utilized as a substitute for root canal irrigants.

摘要

引言

根管治疗成功需要彻底清除根管内的微生物并对根管空间进行三维充填。在根管治疗失败的病例中,[细菌名称未给出]是最常检测到的细菌。微生物可借助化学冲洗予以清除。

目的

开展本研究以评估三果木、印楝和洗必泰根管冲洗剂的抗菌效果。

材料与方法

将[细菌名称未给出](ATCC)细菌培养物在脑心浸液(BHI)肉汤中过夜培养后接种于穆勒-欣顿琼脂平板。采用琼脂孔扩散法测量抗菌抑制作用。将三种研究冲洗剂加入琼脂平板的相应孔中后,于37℃孵育24小时。记录每个孔的细菌抑制圈。对结果进行列表后,进行统计分析。

结果

当三果木和印楝提取物加入洗必泰时,观察到对[细菌名称未给出]的最大抑制圈。

结论

草药三果木和印楝提取物在针对[细菌名称未给出]进行测试时表现出抑制圈。因此,这些冲洗剂可作为根管冲洗剂的替代品。

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本文引用的文献

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Assessment of the Antimicrobial Effectiveness of Herbal Root Canal Irrigants (Propolis, Triphala, and Aloe Vera) and Chlorhexidine Against Enterococcus Faecalis.草药根管冲洗剂(蜂胶、三果木和芦荟)与氯己定对粪肠球菌抗菌效果的评估
Cureus. 2023 Jul 10;15(7):e41628. doi: 10.7759/cureus.41628. eCollection 2023 Jul.
2
Comparative evaluation of antimicrobial efficacy of three herbal irrigants in reducing intracanal E. faecalis populations: An in vitro study.三种草药冲洗剂在减少根管内粪肠球菌数量方面抗菌效果的比较评估:一项体外研究。
J Clin Exp Dent. 2016 Jul 1;8(3):e230-5. doi: 10.4317/jced.52339. eCollection 2016 Jul.
3
Comparative evaluation of antimicrobial effect of herbal root canal irrigants (Morinda citrifolia, Azadirachta indica, Aloe vera) with sodium hypochlorite: An in vitro study.草药根管冲洗剂(巴戟天、印楝、芦荟)与次氯酸钠抗菌效果的比较评价:一项体外研究。
J Int Soc Prev Community Dent. 2016 May-Jun;6(3):196-9. doi: 10.4103/2231-0762.183104. Epub 2016 May 30.
4
In vivo antimicrobial efficacy of 6% Morinda citrifolia, Azadirachta indica, and 3% sodium hypochlorite as root canal irrigants.6%巴戟天、印楝作为根管冲洗剂与3%次氯酸钠的体内抗菌效果。
Eur J Dent. 2015 Oct-Dec;9(4):529-534. doi: 10.4103/1305-7456.172615.