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唾液腺肿瘤病例的回顾性分析:组织学变异与临床结果

A Retrospective Analysis of Salivary Gland Tumor Cases: Histological Variations and Clinical Outcomes.

作者信息

Dolma Kunzes, Issac Anu Sumi, Gupta Renuka, Kumari Achanta Surya, Channe Pallavi P, Venkata Ramanand Oruganti, Managutti Anil

机构信息

Department of ENT, Vardhman Mahavir Medical College and Safdarjung Hospital, New Delhi, India.

Department of Pathology, Dr Somervell Memorial CSI Medical College, Karakonam, Trivandrum, Kerala, India.

出版信息

J Pharm Bioallied Sci. 2024 Jul;16(Suppl 3):S2443-S2445. doi: 10.4103/jpbs.jpbs_296_24. Epub 2024 Jul 31.

Abstract

BACKGROUND

Salivary gland tumors (SGTs) present a diagnostic challenge due to their diverse histological subtypes and variable clinical behavior.

METHODS

This research conducted a retrospective analysis of SGT cases diagnosed and managed at a tertiary care center between 2017 and 2022. Clinical and pathological data were retrieved from medical records and histopathology reports. Statistical analysis was performed to identify factors associated with recurrence and survival outcomes.

RESULTS

A total of 150 SGT cases were included, comprising 70% benign and 30% malignant tumors. Pleomorphic adenoma and adenoid cystic carcinoma were the most prevalent benign and malignant subtypes, respectively. Surgical resection was the primary treatment modality, with varying recurrence rates observed among different treatment groups.

CONCLUSION

The current study provides insights into the histological variations and clinical outcomes of SGTs. Surgical resection remains the mainstay of treatment, with adjuvant therapy reserved for cases with adverse prognostic factors. Further research is needed to optimize therapeutic strategies and improve patient outcomes.

摘要

背景

涎腺肿瘤(SGTs)因其多样的组织学亚型和多变的临床行为而带来诊断挑战。

方法

本研究对2017年至2022年在一家三级医疗中心诊断和治疗的SGT病例进行了回顾性分析。从病历和组织病理学报告中检索临床和病理数据。进行统计分析以确定与复发和生存结果相关的因素。

结果

共纳入150例SGT病例,其中良性肿瘤占70%,恶性肿瘤占30%。多形性腺瘤和腺样囊性癌分别是最常见的良性和恶性亚型。手术切除是主要的治疗方式,不同治疗组的复发率各不相同。

结论

本研究为SGTs的组织学变异和临床结果提供了见解。手术切除仍然是治疗的主要手段,辅助治疗适用于具有不良预后因素的病例。需要进一步研究以优化治疗策略并改善患者预后。

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