Alotay Abdulwahed A
Department of Internal Medicine, College of Medicine, Imam Mohammad Ibn Saud Islamic University (IMSIU), Riyadh, Saudi Arabia.
J Pharm Bioallied Sci. 2024 Jul;16(Suppl 3):S3002-S3004. doi: 10.4103/jpbs.jpbs_449_24. Epub 2024 Jun 20.
A small number of gastrointestinal smooth muscle tumors are caused by leiomyoma, which are uncommon in the colon. Typically, these tumors are benign and asymptomatic. They typically affect middle-aged and older populations. They are uncommon, making up about 3% of gastrointestinal leiomyomas. During a screening colonoscopy, a 52-year-old Saudi male revealed a little, 5-mm ascending colon polyp in this case report. The polyp was transported to the pathology laboratory after being removed using a hot snare polypectomy. The histopathology report confirmed the size of the polyp (5 mm), single, firm, gray-white, polypoid 0.5 cm nodule, and the findings were consistent with inflamed submucosal leiomyoma with inflamed and ulcerated surface. No findings are suggestive of malignant changes. In conclusion, A rare benign tumor, intestinal leiomyoma, can mimic several smooth muscle tumors, especially adnexal masses, making diagnosis difficult. Though nonspecific radiological abnormalities are conceivable, huge size and extra-colic growth increase the likelihood of a diagnosis. Computed tomography (CT) can help identify benign leiomyoma from leiomyosarcoma, but tissue diagnosis is best. Histoimmunopathology is crucial to diagnosis. Small and large colonic leiomyoma polyps can be treated by snare polypectomy and wide surgical excision with follow-up. For some leiomyosarcoma patients, surgery, radiation, and chemotherapy are the main treatments.
少数胃肠道平滑肌瘤由平滑肌瘤引起，在结肠中并不常见。通常，这些肿瘤是良性且无症状的。它们通常影响中年及老年人群。它们并不常见，约占胃肠道平滑肌瘤的3%。在本次病例报告中，一名52岁的沙特男性在结肠镜筛查时发现升结肠有一个5毫米的小息肉。使用热圈套息肉切除术切除息肉后，将其送至病理实验室。组织病理学报告证实息肉大小为5毫米，单个，质地硬，灰白色，息肉样0.5厘米结节，结果与黏膜下平滑肌瘤伴表面炎症和溃疡相符。未发现提示恶性改变的迹象。总之，一种罕见的良性肿瘤——肠道平滑肌瘤，可模仿几种平滑肌肿瘤，尤其是附件肿物，导致诊断困难。尽管可能出现非特异性放射学异常，但巨大尺寸和结肠外生长增加了诊断的可能性。计算机断层扫描（CT）有助于从平滑肌肉瘤中鉴别出良性平滑肌瘤，但组织诊断是最佳的。组织免疫病理学对诊断至关重要。大小结肠平滑肌瘤息肉可通过圈套息肉切除术和广泛手术切除并进行随访治疗。对于一些平滑肌肉瘤患者，手术、放疗和化疗是主要治疗方法。
