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J Pharm Bioallied Sci. 2024 Jul;16(Suppl 3):S2546-S2548. doi: 10.4103/jpbs.jpbs_277_24. Epub 2024 Jul 31.
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本文引用的文献

1
Comparative Study of Antifungal Efficacy of Various Endodontic Irrigants with and without Clotrimazole in Extracted Teeth Inoculated with .不同根管冲洗剂联合克霉唑对感染根管内粪肠球菌的抗菌效果比较
J Contemp Dent Pract. 2020 Dec 1;21(12):1325-1330.
2
Diversity of endodontic microbiota revisited.再探牙髓微生物群的多样性。
J Dent Res. 2009 Nov;88(11):969-81. doi: 10.1177/0022034509346549.
3
Bacterial community profiling of cryogenically ground samples from the apical and coronal root segments of teeth with apical periodontitis.对患有根尖周炎牙齿的根尖和冠根段低温研磨样本进行细菌群落分析。
J Endod. 2009 Apr;35(4):486-92. doi: 10.1016/j.joen.2008.12.022. Epub 2009 Feb 26.
4
The properties and applications of chlorhexidine in endodontics.洗必泰在牙髓病学中的特性与应用。
Int Endod J. 2009 Apr;42(4):288-302. doi: 10.1111/j.1365-2591.2008.01540.x. Epub 2009 Feb 7.
5
Surface tension comparison of four common root canal irrigants and two new irrigants containing antibiotic.
J Endod. 2006 Nov;32(11):1091-3. doi: 10.1016/j.joen.2006.05.008.
6
Root canal irrigants.根管冲洗剂
J Endod. 2006 May;32(5):389-98. doi: 10.1016/j.joen.2005.09.014.

探索疗效与安全性:三级医疗环境下根管治疗中不同冲洗液的比较评估

Exploring Efficacy and Safety: Comparative Evaluation of Different Irrigation Solutions in Root Canal Therapy at a Tertiary Care Setting.

作者信息

Yadav Yesha, Anil C K, Kumar Neshaneni Satish, Batra Divya, Kapur Ishita, Chaturvedi Mudita, Mustafa Mohammed

机构信息

Department of Conservative Dentistry and Endodontics, Army College of Dental Sciences, Hyderabad, Telangana, India.

Department of Conservative Dentistry and Endodontics, Consultant Endodontist, Hyderabad, Telangana, India.

出版信息

J Pharm Bioallied Sci. 2024 Jul;16(Suppl 3):S2546-S2548. doi: 10.4103/jpbs.jpbs_277_24. Epub 2024 Jul 31.

DOI:10.4103/jpbs.jpbs_277_24
PMID:39346432
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11426867/
Abstract

BACKGROUND

In order to completely remove bacteria and debris from the root canal system, root canal treatment (RCT) calls for efficient irrigation methods. There is still a lack of research on the relative safety and efficacy of various irrigation systems in tertiary care settings.

METHODS

Patients receiving RCT at a tertiary care endodontic clinic were included in a prospective comparison research of 150 subjects. One of four irrigation solutions-sodium hypochlorite, chlorhexidine, ethylenediaminetetraacetic acid (EDTA), or a combination of the three-was given to patients at random. Following surgery, microbial decrease and patient-reported pain levels were evaluated.

RESULTS

The analysis showed that there were significant differences ( < 0.05) in microbial decrease between the irrigation solution groups. EDTA, sodium hypochlorite, and chlorhexidine were the next three groups with the biggest mean log decrease in microbial counts, after the combination group. Nonetheless, there were no appreciable variations in the groups' patient-reported pain levels ( > 0.05).

CONCLUSION

Our results imply that microbial reduction in RCT is highly influenced by the irrigation solution selection. Without having an impact on the pain sensations reported by the patients, the combination of irrigation solutions showed higher efficacy in microbial control. These findings highlight how crucial it is to choose an irrigation solution carefully in order to maximize endodontic outcomes in tertiary care settings.

摘要

背景

为了彻底清除根管系统中的细菌和碎屑,根管治疗(RCT)需要有效的冲洗方法。在三级医疗机构中,对于各种冲洗系统的相对安全性和有效性仍缺乏研究。

方法

在一家三级牙髓病诊所接受RCT治疗的患者被纳入一项前瞻性比较研究,共150名受试者。四种冲洗液中的一种——次氯酸钠、氯己定、乙二胺四乙酸(EDTA)或三者的组合——被随机给予患者。手术后,评估微生物减少情况和患者报告的疼痛程度。

结果

分析表明,冲洗液组之间在微生物减少方面存在显著差异(<0.05)。在联合组之后,EDTA、次氯酸钠和氯己定是微生物计数平均对数下降最大的接下来三组。然而,各组患者报告的疼痛程度没有明显差异(>0.05)。

结论

我们的结果表明,根管治疗中微生物的减少受冲洗液选择的影响很大。冲洗液组合在微生物控制方面显示出更高的疗效,而对患者报告的疼痛感没有影响。这些发现凸显了在三级医疗机构中仔细选择冲洗液对于最大化牙髓治疗效果的关键重要性。