Suppr超能文献

抗N-甲基-D-天冬氨酸受体脑炎伴畸胎瘤所致双侧听力丧失:一例报告

Bilateral hearing loss caused by anti-NMDA receptor encephalitis with teratoma: A case report.

作者信息

Zhang Guo-Fang, Liang Tao, Lv Yi-Kun, Luo Zhong, Zhang Jun

机构信息

Department of Neurology Affiliated Hospital of Zunyi Medical University Zunyi China.

出版信息

Ibrain. 2023 Jun 25;10(3):378-384. doi: 10.1002/ibra.12116. eCollection 2024 Fall.

Abstract

Autoimmune encephalitis (AE) is an autoimmune disease in the central nervous system. Clinical manifestations include cognitive dysfunction, psychiatric-behavioral abnormalities, epilepsy, motor disorders, speech disorders, and memory impairment. Some patients do not have the characteristic clinical manifestations of the disease when they see a doctor, so they are easily diagnosed incorrectly. Autoimmune antibodies originate from genetic and acquired factors. Clinical data have found a correlation between ovarian teratoma and autoimmune encephalitis. This case reports a 34-year-old woman who was diagnosed with teratoma-associated anti-N-methyl-D- aspartate receptor-mediated autoimmune encephalitis called anti-N-methyl-D-aspartate receptor encephalitis with bilateral hearing loss in 2021. Through this case report, clinicians will pay attention to autoimmune encephalitis and raise awareness of the specific clinical manifestations of autoimmune encephalitis, and focus on early identification. It means that clinicians should be familiar with the representative clinical manifestations of the disease.

摘要

自身免疫性脑炎(AE)是一种中枢神经系统的自身免疫性疾病。临床表现包括认知功能障碍、精神行为异常、癫痫、运动障碍、言语障碍和记忆损害。部分患者就诊时无该病的特征性临床表现,故易被误诊。自身免疫抗体源于遗传和后天因素。临床资料发现卵巢畸胎瘤与自身免疫性脑炎之间存在关联。本病例报告了一名34岁女性,她于2021年被诊断为畸胎瘤相关的抗N-甲基-D-天冬氨酸受体介导的自身免疫性脑炎,即抗N-甲基-D-天冬氨酸受体脑炎,伴有双侧听力丧失。通过本病例报告,临床医生将关注自身免疫性脑炎,提高对自身免疫性脑炎特定临床表现的认识,并注重早期识别。这意味着临床医生应熟悉该病的典型临床表现。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/070b/11427792/8e09febc5edb/IBRA-10-378-g002.jpg

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验