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胃癌起源的库肯伯格瘤表现为假性梅格斯综合征:一例报告及文献复习

Krukenberg tumor arising from gastric cancer presenting as Pseudo-Meigs' syndrome: a case report and literature review.

作者信息

Qiu Shikang, Jiang Huihui, Ding Hanxiao, Feng Limin

机构信息

Department of Gynecology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.

Department of Clinical Laboratory, Qingdao Central Hospital, University of Health and Rehabilitation Sciences (Qingdao Cancer Hospital), Qingdao, Shandong, China.

出版信息

Front Med (Lausanne). 2024 Sep 13;11:1427568. doi: 10.3389/fmed.2024.1427568. eCollection 2024.

DOI:10.3389/fmed.2024.1427568
PMID:39346945
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11427251/
Abstract

Krukenberg tumor is a relatively uncommon metastatic ovarian cancer, typically presenting with abdominal pain and distension, primarily due to bilateral ovarian involvement. Pseudo-Meigs' syndrome, caused by a Krukenberg tumor originating from gastric cancer, is extremely rare. In this study, we report the case of a 39-year-old woman who presented with unusual manifestations of a Krukenberg tumor, where abdominal distension and dyspnea were the primary symptoms. After surgical treatment, a histopathological examination of the ovary revealed the presence of signet ring cell carcinoma. We concluded that this case coincided with Pseudo-Meigs' syndrome. Clinicians should note that Pseudo-Meigs' syndrome should be considered in patients with Krukenberg tumor, ascites, and pleural effusion, as resection of the tumor may provide long-term palliation.

摘要

库肯勃瘤是一种相对罕见的转移性卵巢癌,通常表现为腹痛和腹胀,主要是由于双侧卵巢受累。由源自胃癌的库肯勃瘤引起的假性梅格斯综合征极为罕见。在本研究中,我们报告了一例39岁女性,该患者表现出库肯勃瘤的不寻常表现,以腹胀和呼吸困难为主要症状。手术治疗后,对卵巢进行组织病理学检查发现存在印戒细胞癌。我们得出结论,该病例符合假性梅格斯综合征。临床医生应注意,对于患有库肯勃瘤、腹水和胸腔积液的患者,应考虑假性梅格斯综合征,因为切除肿瘤可能提供长期缓解。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/97d5/11427251/d1b503c5aac6/fmed-11-1427568-g0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/97d5/11427251/2f5f6a2d13a0/fmed-11-1427568-g0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/97d5/11427251/d1b503c5aac6/fmed-11-1427568-g0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/97d5/11427251/2f5f6a2d13a0/fmed-11-1427568-g0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/97d5/11427251/d1b503c5aac6/fmed-11-1427568-g0002.jpg

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Krukenberg tumor arising from gastric cancer presenting as Pseudo-Meigs' syndrome: a case report and literature review.胃癌起源的库肯伯格瘤表现为假性梅格斯综合征:一例报告及文献复习
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本文引用的文献

1
Secondary amenorrhea as the first presentation of Krukenberg tumor arising from the gastroesophageal junction in a 34-year-old woman: A case report.34岁女性胃食管交界处原发性库肯勃瘤以继发性闭经为首发表现:一例报告
Int J Surg Case Rep. 2024 Apr;117:109472. doi: 10.1016/j.ijscr.2024.109472. Epub 2024 Mar 1.
2
Cd44v6 acts as a directional responding factor in the process of transcoelomic metastasis from gastric carcinoma to Krukenberg tumor.CD44v6 在胃癌腹腔转移至库肯勃瘤的过程中充当定向反应因子。
Expert Rev Mol Diagn. 2023 Jul-Dec;23(7):583-588. doi: 10.1080/14737159.2023.2223981. Epub 2023 Jul 6.
3
A case of death of patient with ovarian fibroma combined with Meigs Syndrome and literature review.
卵巢纤维瘤合并梅格斯综合征患者死亡 1 例并文献复习
Diagn Pathol. 2022 Oct 17;17(1):83. doi: 10.1186/s13000-022-01258-9.
4
Pelvic mass, ascites, hydrothorax: a malignant or benign condition? Meigs syndrome with high levels of CA 125.盆腔肿块、腹水、胸腔积液:恶性还是良性病症?伴有高水平CA 125的梅格斯综合征
Prz Menopauzalny. 2021 Jun;20(2):103-107. doi: 10.5114/pm.2021.106100. Epub 2021 May 25.
5
The diagnosis and outcome of Krukenberg tumors.库肯勃瘤的诊断与预后
J Gastrointest Oncol. 2021 Apr;12(2):226-236. doi: 10.21037/jgo-20-364.
6
Pleural Disease in Women.女性胸膜疾病。
Semin Respir Crit Care Med. 2019 Jun;40(3):402-409. doi: 10.1055/s-0039-1695050. Epub 2019 Sep 16.
7
Glioblastoma metastatic to the ovary, a very different Krukenberg tumor?转移至卵巢的胶质母细胞瘤,一种截然不同的库肯勃瘤?
Pract Radiat Oncol. 2018 Nov-Dec;8(6):373-375. doi: 10.1016/j.prro.2018.04.002. Epub 2018 Apr 7.
8
PD-L1 Expression Predicts a Distinct Prognosis in Krukenberg Tumor with Corresponding Origins.PD-L1 表达可预测具有相应起源的 Krukenberg 肿瘤的独特预后。
J Immunol Res. 2018 May 8;2018:9485285. doi: 10.1155/2018/9485285. eCollection 2018.
9
A rare Krukenberg tumor arising from a primary adenocarcinoma of the small intestine.一种罕见的源于小肠原发性腺癌的库肯勃瘤。
Taiwan J Obstet Gynecol. 2018 Apr;57(2):319-322. doi: 10.1016/j.tjog.2018.02.025.
10
Krukenberg tumors: Seed, route and soil.库肯勃瘤:种子、途径与土壤
Surg Oncol. 2017 Dec;26(4):438-445. doi: 10.1016/j.suronc.2017.09.001. Epub 2017 Sep 12.