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定制化腹膜透析培训项目在降低感染率和退出率方面的有效性:来自新加坡一家医院的见解

Effectiveness of a Customized Peritoneal Dialysis Training Program in Reducing Infection and Dropout Rates: Insights From a Singapore Hospital.

作者信息

Lee Pei Shan, Tay Hui Boon, Luo XiaoHong, Chiang Seow Yean, Loh Sing Ping, Lai Boon Cheok

机构信息

Department of Nephrology, Sengkang General Hospital, Singapore, SGP.

Department of Nursing, Sengkang General Hospital, Singapore, SGP.

出版信息

Cureus. 2024 Aug 28;16(8):e67997. doi: 10.7759/cureus.67997. eCollection 2024 Aug.

Abstract

Introduction Peritoneal dialysis (PD) is an essential home-based treatment for end-stage kidney disease, known for enhancing patients' quality of life and being more cost-effective compared to hemodialysis. However, in Singapore, PD education lacks of standardization, with each unit adopting varied methods based on their own experiences and resources. To address this, our hospital developed a tailored four-day PD training program guided by the International Society for Peritoneal Dialysis guidelines, adapted to meet local needs and resource availability. Methodology This study employed a retrospective cohort design, including all incident adult patients aged 18 years and above who initiated PD at our hospital from September 2018 to July 2023. Data on PD dropout rates and PD-related infection rates, such as PD peritonitis and exit site infection rates, were obtained from electronic medical records. Results This study comprised 99 patients who began PD and completed their PD training program at our hospital between September 2018 and July 2023. Our tailored PD training program successfully reduced dropout rates and maintained infection rates within the International Society for Peritoneal Dialysis guidelines. Specifically, exit site infection rates fluctuated between 0.18 and 0.29 episodes per year, PD peritonitis rates ranged from 0.2 to 0.26 episodes per patient-year, and dropout rates significantly improved from 40% in 2019 to 7% in 2023 (OR = 0.45, 95% CI = 0.49 to 0.84, p = 0.010). Conclusions The tailored PD training program at our hospital effectively reduced PD-related infections and dropout rates among end-stage kidney disease patients. These findings suggest that structured, locally adapted training programs can substantially improve patient outcomes in PD.

摘要

引言

腹膜透析(PD)是终末期肾病的一种重要居家治疗方式,以提高患者生活质量且比血液透析更具成本效益而闻名。然而,在新加坡,腹膜透析教育缺乏标准化,每个单位根据自身经验和资源采用不同的方法。为解决这一问题,我院根据国际腹膜透析学会指南制定了一个为期四天的量身定制的腹膜透析培训项目,以适应本地需求和资源可用性。

方法

本研究采用回顾性队列设计,纳入了2018年9月至2023年7月在我院开始进行腹膜透析的所有18岁及以上的成年新发病例患者。从电子病历中获取腹膜透析退出率和腹膜透析相关感染率的数据,如腹膜透析腹膜炎和出口处感染率。

结果

本研究包括99例在2018年9月至2023年7月期间在我院开始腹膜透析并完成腹膜透析培训项目的患者。我们量身定制的腹膜透析培训项目成功降低了退出率,并将感染率维持在国际腹膜透析学会指南范围内。具体而言,出口处感染率每年在0.18至0.29次发作之间波动,腹膜透析腹膜炎发生率为每位患者每年0.2至0.26次发作,退出率从2019年的40%显著改善至2023年的7%(OR = 0.45,95% CI = 0.49至0.84,p = 0.010)。

结论

我院量身定制的腹膜透析培训项目有效降低了终末期肾病患者的腹膜透析相关感染和退出率。这些发现表明,结构化的、因地制宜的培训项目可以显著改善腹膜透析患者的治疗效果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e45a/11437699/8e8541676462/cureus-0016-00000067997-i01.jpg

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