系统性红斑狼疮中的心脏传导缺陷
Cardiac Conduction Defects in Systemic Lupus Erythematosus.
作者信息
Butt Shayan, Kiran Simra, Qadir Nida, Menghani Divya, Tanzeem Hammad
机构信息
Internal Medicine, Baptist Memorial Hospital, Oxford, USA.
Pulmonology and Critical Care, University of Cincinnati Medical Center, Cincinnati, USA.
出版信息
Cureus. 2020 Oct 10;12(10):e10882. doi: 10.7759/cureus.10882.
Abstract
Systemic autoimmune conditions may cause morbidity and mortality. Systemic lupus erythematosus (SLE) is a prominent example of such diseases. It can result in conduction abnormalities due to accelerated atherosclerosis, vasculitis, or autoantibodies-induced myocarditis. Cardiac conduction abnormalities may produce sinus tachycardia, sinus bradycardia, prolonged QT intervals, atrial fibrillation, or atrioventricular (AV) nodal blocks. Neonatal lupus is sometimes associated with anti-Ro/SSA and anti-La/SSB antibodies, but their role remains a matter of controversy in adults.
摘要
全身性自身免疫性疾病可能导致发病和死亡。系统性红斑狼疮（SLE）就是这类疾病的一个突出例子。它可因动脉粥样硬化加速、血管炎或自身抗体诱导的心肌炎而导致传导异常。心脏传导异常可能产生窦性心动过速、窦性心动过缓、QT间期延长、心房颤动或房室（AV）结阻滞。新生儿狼疮有时与抗Ro/SSA和抗La/SSB抗体有关，但其在成人中的作用仍存在争议。
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