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首发重症肌无力危象所致急性呼吸衰竭

Acute Respiratory Failure Due to Inaugural Myasthenia Crisis.

作者信息

Ntawuruhunga Irene N, Nougon Gervais

机构信息

Emergency Medicine, La Clinique Saint-Luc Bouge (SLBO), Namur, BEL.

出版信息

Cureus. 2024 Aug 29;16(8):e68090. doi: 10.7759/cureus.68090. eCollection 2024 Aug.

DOI:10.7759/cureus.68090
PMID:39347200
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11437520/
Abstract

Myasthenia gravis is a rare disease that can lead to a serious condition known as myasthenic crisis (MC). The diagnosis of MC is clinical and relies on the presence of typical symptoms that can be absent, emphasizing the importance of attracting the attention of emergency physicians to this rare cause of respiratory failure. We present the case of a 66-year-old woman presenting to the emergency department with a history of recent muscle fatigue and dehydration who developed acute respiratory failure requiring mechanical ventilation.

摘要

重症肌无力是一种罕见疾病,可导致一种称为重症肌无力危象(MC)的严重情况。MC的诊断基于临床,依赖于典型症状的存在,但这些症状可能不存在,这凸显了引起急诊医生对这种罕见的呼吸衰竭病因予以关注的重要性。我们报告了一例66岁女性患者,她因近期肌肉疲劳和脱水病史就诊于急诊科,随后发展为需要机械通气的急性呼吸衰竭。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0c6d/11437520/dd1c3ffd7b49/cureus-0016-00000068090-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0c6d/11437520/c839cee3cde2/cureus-0016-00000068090-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0c6d/11437520/dd1c3ffd7b49/cureus-0016-00000068090-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0c6d/11437520/c839cee3cde2/cureus-0016-00000068090-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0c6d/11437520/dd1c3ffd7b49/cureus-0016-00000068090-i02.jpg

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本文引用的文献

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Autoimmune myasthenia gravis and COVID-19. A case report-based review.自身免疫性重症肌无力与 COVID-19。基于病例报告的综述。
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Myasthenia gravis in current status: epidemiology, types, etiology, pathophysiology, symptoms, diagnostic tests, prevention, treatment, and complications - correspondence.重症肌无力的现状:流行病学、类型、病因、病理生理学、症状、诊断测试、预防、治疗及并发症——通信
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The humanistic burden of myasthenia gravis: A systematic literature review.
重症肌无力的人文负担:系统文献回顾。
J Neurol Sci. 2022 Jun 15;437:120268. doi: 10.1016/j.jns.2022.120268. Epub 2022 Apr 21.
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Acetylcholinesterase Inhibitors in Myasthenic Crisis: A Systematic Review of Observational Studies.乙酰胆碱酯酶抑制剂在肌无力危象中的应用:一项观察性研究的系统评价。
Neurocrit Care. 2021 Oct;35(2):528-544. doi: 10.1007/s12028-021-01259-4. Epub 2021 Jul 22.
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Acute Myasthenia Crisis: A Critical Emergency Department Differential.急性重症肌无力危象:急诊科的关键鉴别诊断
Cureus. 2020 Aug 15;12(8):e9760. doi: 10.7759/cureus.9760.
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Perianesthetic Implications and Considerations for Myasthenia Gravis.重症肌无力围麻醉期的影响及注意事项
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Critical care in the emergency department: acute respiratory failure.急诊科的重症监护:急性呼吸衰竭。
Emerg Med J. 2011 Feb;28(2):94-7. doi: 10.1136/emj.2005.030643. Epub 2010 Nov 26.