Dhabalia Rishabh, Kashikar Shivali V, Parihar Pratapsingh, Nunna Bhagyasri, Bothara Shivani S, Reddy Lucky Srivani
Radiodiagnosis, Jawaharlal Nehru Medical College, Datta Meghe Institute of Higher Education & Research, Wardha, IND.
Obstetrics and Gynaecology, Jawaharlal Nehru Medical College, Datta Meghe Institute of Higher Education & Research, Wardha, IND.
Cureus. 2024 Aug 30;16(8):e68197. doi: 10.7759/cureus.68197. eCollection 2024 Aug.
Background T2-weighted hyperintensities in the spinal cord are crucial markers for diagnosing a range of spinal cord pathologies. This study explores the prevalence, causes, and implications of these hyperintensities in patients with spinal cord injuries at a tertiary care hospital in Central India. The research aims to assess the utility of MRI in detecting T2-weighted hyperintensities in the spinal cord and to analyze the associated clinical and radiological characteristics. Materials and methods A prospective observational study was conducted involving patients referred to the Department of Radiodiagnosis at Acharya Vinoba Bhave Rural Hospital (AVBRH), Sawangi (Wardha), with suspected or confirmed spinal cord injuries. Advanced MRI techniques, including T2-weighted imaging, were used for the evaluation. The study analyzed demographic data, clinical features, and MRI findings to identify common causes and patterns of T2-weighted hyperintensities. Results The study revealed that T2-weighted hyperintensities were present in 54 (72%) MRI scans of patients with spinal cord pathologies at our tertiary care hospital in Central India. Among these, multiple sclerosis was the most frequent diagnosis, accounting for 27 (35%) cases. Traumatic spinal cord injuries were observed in 25% (n=19) of patients, while transverse myelitis was found in 15 (20%). The remaining 15 (20%) included a variety of other conditions, such as infections and tumors. The extent and distribution of T2-weighted hyperintensities varied significantly among different diagnoses, with multiple sclerosis and transverse myelitis demonstrating a more extensive involvement compared to trauma-related cases. Conclusion MRI is a valuable tool for diagnosing and understanding the underlying causes of spinal cord hyperintensities. The study highlights the need for targeted diagnostic and therapeutic approaches based on MRI findings to improve patient outcomes in spinal cord injuries.
背景 脊髓T2加权高信号是诊断一系列脊髓疾病的关键标志物。本研究探讨了印度中部一家三级护理医院脊髓损伤患者中这些高信号的患病率、病因及影响。该研究旨在评估MRI在检测脊髓T2加权高信号方面的效用,并分析相关的临床和放射学特征。
材料与方法 开展了一项前瞻性观察性研究,纳入了转诊至萨旺吉(瓦尔达)阿查里亚·维诺巴·巴韦农村医院(AVBRH)放射诊断科、疑似或确诊脊髓损伤的患者。采用包括T2加权成像在内的先进MRI技术进行评估。该研究分析了人口统计学数据、临床特征和MRI结果,以确定T2加权高信号的常见病因和模式。
结果 研究显示,在我们印度中部三级护理医院的脊髓疾病患者的54份(72%)MRI扫描中存在T2加权高信号。其中,多发性硬化症是最常见的诊断,占27例(35%)。25%(n = 19)的患者观察到创伤性脊髓损伤,而15例(20%)发现横贯性脊髓炎。其余15例(20%)包括各种其他疾病,如感染和肿瘤。不同诊断之间T2加权高信号的范围和分布差异显著,与创伤相关病例相比,多发性硬化症和横贯性脊髓炎的受累范围更广。
结论 MRI是诊断和了解脊髓高信号潜在病因的有价值工具。该研究强调需要根据MRI结果采取针对性的诊断和治疗方法,以改善脊髓损伤患者的预后。